“弦征”-三联药物治疗班氏丝虫病感染后出现前臂急性淋巴管炎。

IF 1.2 4区 医学 Q4 INFECTIOUS DISEASES
Vijesh Sreedhar Kuttiatt, Manju Rahi, Jambulingam Purushothaman
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引用次数: 0

摘要

大量给药消除淋巴丝虫病后的局部不良事件往往是自限性的。然而,它们是参与者非常关注的问题,如果管理不当,可能会影响社区药物依从性。在这里,我们报告了一个相当罕见的不良事件,“串征”在南印度妇女班氏丝虫病感染治疗三联药物方案(ida -伊维菌素,乙基卡马嗪和阿苯达唑)。弦征是急性淋巴管炎的表现,表现为淋巴管肿胀和炎症引起的索状皮下肿胀,一般认为是由于化疗后成虫死亡所致。卫生保健工作者需要意识到这种不寻常的局部不良事件,可能发生在丙二醛清除LF后。不良事件的及时医疗管理和健康教育是确保在大规模用药计划中坚持用药的重要因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
"String sign"- acute lymphangitis in the forearm following triple drug therapy for bancroftian filarial infection.

Localized adverse events following mass drug administration for lymphatic filariasis elimination are often self-limiting. However, they are of significant concern to the participants and may affect community drug compliance if not managed appropriately. Here, we report a rather uncommon adverse event, the 'string sign' in a south Indian woman with bancroftian filarial infection treated with triple drug regimen (IDA-Ivermectin, Diethylcarbamazine and Albendazole). String sign is the manifestation of acute lymphangitis as a cordlike subcutaneous swelling due to the swollen and inflamed lymphatic vessel, which is believed to occur due to the death of the adult filarial worms subsequent to chemotherapy. Health care workers need to be aware of such unusual localized adverse events that may occur following MDA for LF elimination. Prompt medical management of adverse events and health education are important to ensure adherence to drug consumption during mass drug administration program.

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来源期刊
Journal of Vector Borne Diseases
Journal of Vector Borne Diseases INFECTIOUS DISEASES-PARASITOLOGY
CiteScore
0.90
自引率
0.00%
发文量
89
审稿时长
>12 weeks
期刊介绍: National Institute of Malaria Research on behalf of Indian Council of Medical Research (ICMR) publishes the Journal of Vector Borne Diseases. This Journal was earlier published as the Indian Journal of Malariology, a peer reviewed and open access biomedical journal in the field of vector borne diseases. The Journal publishes review articles, original research articles, short research communications, case reports of prime importance, letters to the editor in the field of vector borne diseases and their control.
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