Anne-Laure Faucon, Helena Rydell, Maria Stendahl, Gunilla Welander, Torbjörn Lundgren, Karl-Göran Prûtz, Staffan Schön, Ursa Bonnevier, Aline Kåveryd Hult, Håkan Hedman, Frida Fondelius, Mårten Segelmark, Marie Evans
{"title":"瑞典肾脏登记：所有阶段慢性肾脏疾病的全国性登记。","authors":"Anne-Laure Faucon, Helena Rydell, Maria Stendahl, Gunilla Welander, Torbjörn Lundgren, Karl-Göran Prûtz, Staffan Schön, Ursa Bonnevier, Aline Kåveryd Hult, Håkan Hedman, Frida Fondelius, Mårten Segelmark, Marie Evans","doi":"10.1093/ckj/sfaf238","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>National registries that capture patients with chronic kidney disease (CKD) across all stages are scarce. We present here the Swedish Renal Registry (SRR), a nationwide prospective register covering the whole spectrum of CKD.</p><p><strong>Methods: </strong>Created in 1991, SRR enrolls CKD patients referred to adult nephrologist care (non-dialysis CKD [ND-CKD], kidney transplantation, maintenance dialysis), with an overall coverage of nearly all nephrology clinics in Sweden. SRR encompasses several interconnected databases in which longitudinal clinical, biological, kidney-related, patient-reported data, as well as provider-level information are collected. This report presents the design of the registry, as well as patients characteristics and temporal trends between 2008 and 2021.</p><p><strong>Results: </strong>A total of 45 590 new ND-CKD patients [72 years, 16 656 (36%) women, eGFR 26 ml/min per 1.73 m²], and 8829 incident kidney transplant recipients (51 years, 35% women) were enrolled in SRR between 2008 and 2021. SRR also included 16 034 new patients [68 years, 5420 (34%) women] on maintenance dialysis [70% hemodialysis (HD), 30% peritoneal dialysis (PD)]. Between 2015 and 2021, 4753 patients [59 years, 1884 (40%) women, eGFR 37 ml/min per 1.73 m²] had a registered kidney biopsy. We observed a decrease in HD incidence (69% to 60%, <i>P</i> for trend <.01) and an increase in PD incidence (26% to 32%, <i>P</i> < .01) and pre-emptive transplantation (4.7% to 7.5%, <i>P</i> < .01). The prevalence of comorbidities is high in all CKD stages and increase as eGFR declines. While nephroangiosclerosis and diabetic kidney disease are the most common etiologies, glomerulonephritis are the most frequent diagnoses in biopsied and transplanted patients.</p><p><strong>Conclusion: </strong>The SRR is a nationwide register which aims to contribute to address gaps in our understanding of CKD, to identify important challenges and health priorities, evaluate real-life clinical management and analyze international variations, improve health outcomes, improve quality of life, and reduce the burden of CKD.</p>","PeriodicalId":10435,"journal":{"name":"Clinical Kidney Journal","volume":"18 9","pages":"sfaf238"},"PeriodicalIF":4.6000,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421726/pdf/","citationCount":"0","resultStr":"{\"title\":\"The Swedish Renal Registry: a nationwide registry for chronic kidney disease of all stages.\",\"authors\":\"Anne-Laure Faucon, Helena Rydell, Maria Stendahl, Gunilla Welander, Torbjörn Lundgren, Karl-Göran Prûtz, Staffan Schön, Ursa Bonnevier, Aline Kåveryd Hult, Håkan Hedman, Frida Fondelius, Mårten Segelmark, Marie Evans\",\"doi\":\"10.1093/ckj/sfaf238\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>National registries that capture patients with chronic kidney disease (CKD) across all stages are scarce. We present here the Swedish Renal Registry (SRR), a nationwide prospective register covering the whole spectrum of CKD.</p><p><strong>Methods: </strong>Created in 1991, SRR enrolls CKD patients referred to adult nephrologist care (non-dialysis CKD [ND-CKD], kidney transplantation, maintenance dialysis), with an overall coverage of nearly all nephrology clinics in Sweden. SRR encompasses several interconnected databases in which longitudinal clinical, biological, kidney-related, patient-reported data, as well as provider-level information are collected. This report presents the design of the registry, as well as patients characteristics and temporal trends between 2008 and 2021.</p><p><strong>Results: </strong>A total of 45 590 new ND-CKD patients [72 years, 16 656 (36%) women, eGFR 26 ml/min per 1.73 m²], and 8829 incident kidney transplant recipients (51 years, 35% women) were enrolled in SRR between 2008 and 2021. SRR also included 16 034 new patients [68 years, 5420 (34%) women] on maintenance dialysis [70% hemodialysis (HD), 30% peritoneal dialysis (PD)]. Between 2015 and 2021, 4753 patients [59 years, 1884 (40%) women, eGFR 37 ml/min per 1.73 m²] had a registered kidney biopsy. We observed a decrease in HD incidence (69% to 60%, <i>P</i> for trend <.01) and an increase in PD incidence (26% to 32%, <i>P</i> < .01) and pre-emptive transplantation (4.7% to 7.5%, <i>P</i> < .01). The prevalence of comorbidities is high in all CKD stages and increase as eGFR declines. While nephroangiosclerosis and diabetic kidney disease are the most common etiologies, glomerulonephritis are the most frequent diagnoses in biopsied and transplanted patients.</p><p><strong>Conclusion: </strong>The SRR is a nationwide register which aims to contribute to address gaps in our understanding of CKD, to identify important challenges and health priorities, evaluate real-life clinical management and analyze international variations, improve health outcomes, improve quality of life, and reduce the burden of CKD.</p>\",\"PeriodicalId\":10435,\"journal\":{\"name\":\"Clinical Kidney Journal\",\"volume\":\"18 9\",\"pages\":\"sfaf238\"},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2025-08-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421726/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Kidney Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/ckj/sfaf238\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/9/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Kidney Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/ckj/sfaf238","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
The Swedish Renal Registry: a nationwide registry for chronic kidney disease of all stages.
Background: National registries that capture patients with chronic kidney disease (CKD) across all stages are scarce. We present here the Swedish Renal Registry (SRR), a nationwide prospective register covering the whole spectrum of CKD.
Methods: Created in 1991, SRR enrolls CKD patients referred to adult nephrologist care (non-dialysis CKD [ND-CKD], kidney transplantation, maintenance dialysis), with an overall coverage of nearly all nephrology clinics in Sweden. SRR encompasses several interconnected databases in which longitudinal clinical, biological, kidney-related, patient-reported data, as well as provider-level information are collected. This report presents the design of the registry, as well as patients characteristics and temporal trends between 2008 and 2021.
Results: A total of 45 590 new ND-CKD patients [72 years, 16 656 (36%) women, eGFR 26 ml/min per 1.73 m²], and 8829 incident kidney transplant recipients (51 years, 35% women) were enrolled in SRR between 2008 and 2021. SRR also included 16 034 new patients [68 years, 5420 (34%) women] on maintenance dialysis [70% hemodialysis (HD), 30% peritoneal dialysis (PD)]. Between 2015 and 2021, 4753 patients [59 years, 1884 (40%) women, eGFR 37 ml/min per 1.73 m²] had a registered kidney biopsy. We observed a decrease in HD incidence (69% to 60%, P for trend <.01) and an increase in PD incidence (26% to 32%, P < .01) and pre-emptive transplantation (4.7% to 7.5%, P < .01). The prevalence of comorbidities is high in all CKD stages and increase as eGFR declines. While nephroangiosclerosis and diabetic kidney disease are the most common etiologies, glomerulonephritis are the most frequent diagnoses in biopsied and transplanted patients.
Conclusion: The SRR is a nationwide register which aims to contribute to address gaps in our understanding of CKD, to identify important challenges and health priorities, evaluate real-life clinical management and analyze international variations, improve health outcomes, improve quality of life, and reduce the burden of CKD.
期刊介绍：
About the Journal
Clinical Kidney Journal: Clinical and Translational Nephrology (ckj), an official journal of the ERA-EDTA (European Renal Association-European Dialysis and Transplant Association), is a fully open access, online only journal publishing bimonthly. The journal is an essential educational and training resource integrating clinical, translational and educational research into clinical practice. ckj aims to contribute to a translational research culture among nephrologists and kidney pathologists that helps close the gap between basic researchers and practicing clinicians and promote sorely needed innovation in the Nephrology field. All research articles in this journal have undergone peer review.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
