同色色素作为天然抗氧化剂的理化性质

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI:10.1007/s11172-025-4731-2

A. E. Dontsov, M. A. Yakovleva, M. A. Ostrovsky

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引用次数: 0

摘要

单色色素是一种天然色素，存在于无脊椎动物的眼睛和皮肤中，具有伪装、遮光和抗氧化应激的作用。本研究的对象是从指挥官鱿鱼皮肤中获得的同色体。研究了同色色素的理化性质、抗氧化活性和抗糖化活性。采用鲁米诺化学发光猝灭法评价了共色剂的抗氧化活性。通过果糖对牛血清白蛋白糖基化的抑制程度来评价同色酶的抗糖化活性。结果发现，共色剂具有较高的抗氧化作用（IC50 = 32µg mL - 1）和抗糖化作用（IC50 = 40µg mL - 1）。人们认为，从廉价原料中获得的天然无毒的同色色素可以用于食品工业以及与氧化应激发展相关的疾病的预防和治疗。

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Physicochemical properties of ommochromes as natural antioxidants

Ommochromes are natural pigments occurring in the eyes and skin of invertebrate animals that provide camouflage, light shielding and protection against oxidative stress. The object of this study was ommochromes obtained from the skin of the Commander squid. The aim of the work was to study the physicochemical properties, antioxidant and antiglycation activity of ommochromes. The antioxidant activity of ommochromes was evaluated by the luminol chemiluminescence quenching method. The antiglycation activity of ommochromes was assessed by the degree of inhibition of glycosylation of bovine serum albumin with fructose. It was found that ommochromes demonstrated relatively high antioxidant (IC₅₀ = 32 µg mL⁻¹) and antiglycation (IC₅₀ = 40 µg mL⁻¹) effects. It is assumed that natural non-toxic ommochromes from cheap raw materials can be used in the food industry as well as for the prevention and treatment of the diseases associated with oxidative stress development.

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.