具有金属螯合基团的碳菁作为诊断和治疗的有前途的工具

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI:10.1007/s11172-025-4711-6

I. A. Doroshenko, N. V. Shmychkov, A. O. Govtvan, A. V. Shik, M. K. Beklemishev, T. A. Podrugina

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引用次数: 0

摘要

讨论了具有络合基团的碳菁作为小分子和金属离子传感器的应用。络合碳菁能够强而选择性地与分析物结合，从而产生可靠的荧光响应，这对于传感器系统的发展和细胞过程的研究是有希望的。新型功能化碳菁的合成不仅可以检测金属，还可以检测低浓度的有机化合物，这对人体健康诊断和监测具有重要意义。

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Carbocyanines with metal chelating groups as promising tools for diagnostics and therapy

The application of carbocyanines with complexing groups as sensors for small molecules and metal ions is considered. Complexing carbocyanines capable of binding strongly and selectively to analytes to generate a reliable fluorescent response are promising for the development of sensor systems and study of cellular processes. The synthesis of new functionalized carbocyanines extends a possibility of detecting not only metals but also organic compounds in low concentrations, which is important for human health diagnostics and monitoring.

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.