可持续电化学获取α -硫氰酸酯酮：利用硫氰酸铵的无金属方案

IF 2.7 3区化学 Q2 CHEMISTRY, ORGANIC

European Journal of Organic Chemistry Pub Date : 2025-09-11 DOI:10.1002/ejoc.202500679

Peng Zhang, Fanmin Liu, Chao Qian, Shaodong Zhou

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引用次数: 0

摘要

报道了一种稳定、环保的由芳香酮合成α‐硫氰酸酮的电化学方法。该方案利用硫氰酸铵作为硫氰酸盐源和支撑电解质，在具有铂电极和乙腈/水/硫酸溶剂体系的未分裂电池中。这种无金属催化剂的转化过程在温和的条件下进行，表现出广泛的底物范围、优异的官能团相容性和克级操作的适应性。开发的方法为获取这些有价值的硫氰化羰基化合物提供了一种可持续和实用的替代方法，解决了传统氧化方法的局限性。

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Sustainable Electrochemical Access to α‐Thiocyanate Ketones: A Metal‐Free Protocol Utilizing Ammonium Thiocyanate

A robust and environmentally benign electrochemical method for the synthesis of α‐thiocyanate ketones from aromatic ketones is reported. The protocol utilizes ammonium thiocyanate as both the thiocyanate source and supporting electrolyte in an undivided cell with platinum electrodes and an acetonitrile/water/sulfuric acid solvent system. This metal‐catalyst‐free transformation proceeds under mild conditions, exhibiting broad substrate scope, excellent functional group compatibility, and amenability to gram‐scale operations. The developed approach offers a sustainable and practical alternative for accessing these valuable thiocyanated carbonyl compounds, addressing limitations of conventional oxidative methods.

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来源期刊

European Journal of Organic Chemistry 化学-有机化学

CiteScore

5.40

自引率

3.60%

发文量

752

审稿时长

1 months

期刊介绍： The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry: Liebigs Annalen Bulletin des Sociétés Chimiques Belges Bulletin de la Société Chimique de France Gazzetta Chimica Italiana Recueil des Travaux Chimiques des Pays-Bas Anales de Química Chimika Chronika Revista Portuguesa de Química ACH—Models in Chemistry Polish Journal of Chemistry.