对“甘油三酯-葡萄糖体重指数与原发性高血压患者靶器官损害的关联：一项回顾性队列研究”的评论。

IF 2.5 3区医学 Q2 PERIPHERAL VASCULAR DISEASE

Journal of Clinical Hypertension Pub Date : 2025-09-11 DOI:10.1111/jch.70135

Naghmeh Ziaie, Mohsen Mohammadi, Mohammad Barary, Pouya Tayebi, Soheil Ebrahimpour

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引用次数: 0

摘要

综上所述，作者对高血压代谢介导的器官损伤进行了讨论。未来的研究应优先考虑使用连续的TyG-BMI和预先计划的协变量进行时间到事件建模，标准化TOD定义（例如，基于egfr的肾脏标准），考虑监测强度，并使用透明的校准和决策分析指标进行外部验证。这些步骤将决定TyG-BMI是否为原发性高血压的风险评估增加了可操作的价值。Naghmeh Ziaie：调查，写作-原稿准备。莫森·穆罕默迪：调查、写作——原稿准备。Mohammad Barary：调查，写作-原稿准备，写作-审查和编辑。poya Tayyebi：调查、写作——原稿准备。Soheil Ebrahimpour：调查，监督，写作-原稿准备。所有作者都对这项工作做出了重大贡献，并批准了手稿的最终版本。他们的贡献符合国际医学期刊编辑委员会的最新指导方针。作者没有什么可报告的。作者没有什么可报告的。作者声明无利益冲突。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Commentary on “Association of Triglyceride-Glucose Body Mass Index With Target Organ Damage in Essential Hypertension: A Retrospective Cohort Study”

Dear Editor,

In summary, the authors advance the discussion on metabolically mediated organ injury in hypertension. Future studies should prioritize time-to-event modeling with continuous TyG-BMI and preplanned covariates, standardize TOD definitions (e.g., eGFR-based renal criteria), account for surveillance intensity, and perform external validation with transparent calibration and decision-analytic metrics. These steps will determine whether TyG-BMI adds actionable value to risk assessment in essential hypertension.

Naghmeh Ziaie: investigation, writing – original draft preparation. Mohsen Mohammadi: investigation, writing – original draft preparation. Mohammad Barary: investigation, writing – original draft preparation, writing – review and editing. Pouya Tayyebi: investigation, writing – original draft preparation. Soheil Ebrahimpour: investigation, supervision, writing – original draft preparation. All authors contributed significantly to the work and approved the final version of the manuscript. Their contributions align with the latest guidelines of the International Committee of Medical Journal Editors.

The authors have nothing to report.

The authors declare no conflicts of interest.

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来源期刊

Journal of Clinical Hypertension PERIPHERAL VASCULAR DISEASE-

CiteScore

5.80

自引率

7.10%

发文量

191

审稿时长

4-8 weeks

期刊介绍： The Journal of Clinical Hypertension is a peer-reviewed, monthly publication that serves internists, cardiologists, nephrologists, endocrinologists, hypertension specialists, primary care practitioners, pharmacists and all professionals interested in hypertension by providing objective, up-to-date information and practical recommendations on the full range of clinical aspects of hypertension. Commentaries and columns by experts in the field provide further insights into our original research articles as well as on major articles published elsewhere. Major guidelines for the management of hypertension are also an important feature of the Journal. Through its partnership with the World Hypertension League, JCH will include a new focus on hypertension and public health, including major policy issues, that features research and reviews related to disease characteristics and management at the population level.