Cosmosis: a metaphorical bridge connecting the metaphysical cosmos and physiological osmosis.

In this article, "Cosmosis" introduces a newly coined metaphorical term that illustrates conceptual parallels between the physiological process of osmosis and the expansive dynamics of the cosmos. Designed as an interdisciplinary teaching framework, Cosmosis provides a novel way to link cellular homeostasis with cosmological principles such as entropy, space-time curvature, and dark energy. By drawing on core physiological terms such as concentration gradients, osmotic pressure, aquaporins, and membrane selectivity, Cosmosis offers an analogy that may spark curiosity, support integrative thinking, and encourage cross-disciplinary dialogue in physiology and biochemistry education.NEW & NOTEWORTHY Cosmosis presents a novel metaphor linking physiological osmosis with cosmic expansion. By integrating concepts from thermodynamics, membrane transport, and cosmology, the model equips educators with a tool to make abstract physiological and universal processes more engaging. This cross-disciplinary framework enriches physiology and biochemistry education by reinforcing shared physical principles and encouraging a unified view of the cellular and cosmic realms.