心脏再同步化治疗辅助心室辅助装置外植于婴儿心肌病和左束支传导阻滞。

IF 1.4 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Anila A Chaudhary, Chandra Srinivasan, Katsuhide Maeda, Aaron G DeWitt, Catherine Montgomery, Radhika Rastogi, Matthew J O'Connor, Jonathan J Edwards, Humera Ahmed, Kimberly Y Lin, Joseph W Rossano, Carol Wittlieb-Weber, Jonathan B Edelson
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引用次数: 0

摘要

两名先前健康的婴儿表现为严重的左心室扩张(LV)和严重的左心室功能减退。初始心电图显示左束支阻滞(LBBB),超声心动图显示室间隔壁运动异常。两例患者均使用Berlin Heart EXCOR左心室辅助装置(LVAD)。连续LVAD降压试验显示左室功能改善,尽管由于LBBB存在持续明显的室间隔运动障碍。考虑到持续的非同步化,两人都成功地进行了LVAD移植和心外膜导联放置,以进行双心室心脏再同步化治疗(CRT)。LVAD移植在这个年龄组是罕见的。这些病例强调CRT作为一种策略,可能有助于在有左脑卒中和超声心动图显示不同步的患者中成功移植心室辅助装置。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cardiac Resynchronization Therapy to Aid Ventricular Assist Device Explantation in Infants with Cardiomyopathy and Left Bundle Branch Block.

Two previously healthy infants presented with severely dilated left ventricles (LV) and severely diminished left ventricular function. Their initial ECGs demonstrated a left bundle branch block (LBBB) with evidence of dyskinetic septal wall motion on serial echocardiograms. Both were supported with a Berlin Heart EXCOR left ventricular assist device (LVAD). Serial LVAD turn down trials demonstrated improvement in LV function, though with ongoing pronounced septal dyskinesis due to the LBBB. Both underwent successful LVAD explantation with simultaneous epicardial lead placement for biventricular cardiac resynchronization therapy (CRT) given the ongoing dyssynchrony. LVAD explantation in this age group is rare. These cases highlight CRT as a strategy which may aid in the successful explant of ventricular assist devices in select patients who have LBBB and evidence of dyssynchrony by echocardiogram.

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来源期刊
Pediatric Cardiology
Pediatric Cardiology 医学-小儿科
CiteScore
3.30
自引率
6.20%
发文量
258
审稿时长
12 months
期刊介绍: The editor of Pediatric Cardiology welcomes original manuscripts concerning all aspects of heart disease in infants, children, and adolescents, including embryology and anatomy, physiology and pharmacology, biochemistry, pathology, genetics, radiology, clinical aspects, investigative cardiology, electrophysiology and echocardiography, and cardiac surgery. Articles which may include original articles, review articles, letters to the editor etc., must be written in English and must be submitted solely to Pediatric Cardiology.
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