人工智能驱动的制药实践中的关系问责:对偏见、不公平和结构性损害的伦理方法。

IF 3.4 2区 哲学 Q1 ETHICS
Irfan Biswas
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引用次数: 0

摘要

人工智能(AI)与制药实践的整合引发了严重的伦理问题,包括算法偏见、数据商品化和全球卫生不公平。虽然现有的人工智能伦理框架强调透明度和公平性,但它们往往忽视了与种族、性别和社会经济地位相关的结构性脆弱性。本文引入了关系问责制——一个女权主义伦理框架——来批评人工智能驱动的制药实践,认为企业对有偏见的算法的依赖加剧了设计上的不平等。通过辉瑞与ibm沃森的免疫肿瘤学合作以及b谷歌DeepMind与国家卫生服务合作的案例研究,我们展示了人工智能如何加剧药物定价、获取和开发方面的差距。我们提出了一条将有偏见的训练数据与不公平的健康结果联系起来的因果途径,并得到人工智能驱动的价格歧视和排他性临床试验招募算法的经验证据的支持。提出了包括算法审计和以股权为中心的数据治理在内的政策解决方案,以重新调整人工智能与道德要求的关系。这项工作将女权主义生物伦理学和人工智能治理联系起来,为解决医疗保健创新中的结构性危害提供了一个新的视角。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relational accountability in AI-driven pharmaceutical practices: an ethics approach to bias, inequity and structural harm.

The integration of artificial intelligence (AI) into pharmaceutical practices raises critical ethical concerns, including algorithmic bias, data commodification and global health inequities. While existing AI ethics frameworks emphasise transparency and fairness, they often overlook structural vulnerabilities tied to race, gender and socioeconomic status. This paper introduces relational accountability-a feminist ethics framework-to critique AI-driven pharmaceutical practices, arguing that corporate reliance on biased algorithms exacerbates inequalities by design. Through case studies of Pfizer-IBM Watson's immuno-oncology collaboration and Google DeepMind's National Health Service partnership, we demonstrate how AI entrenches disparities in drug pricing, access and development. We propose a causal pathway linking biased training data to inequitable health outcomes, supported by empirical evidence of AI-driven price discrimination and exclusionary clinical trial recruitment algorithms. Policy solutions, including algorithmic audits and equity-centred data governance, are advanced to realign AI with the ethical imperative. This work bridges feminist bioethics and AI governance, offering a novel lens to address structural harm in healthcare innovation.

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来源期刊
Journal of Medical Ethics
Journal of Medical Ethics 医学-医学:伦理
CiteScore
7.80
自引率
9.80%
发文量
164
审稿时长
4-8 weeks
期刊介绍: Journal of Medical Ethics is a leading international journal that reflects the whole field of medical ethics. The journal seeks to promote ethical reflection and conduct in scientific research and medical practice. It features articles on various ethical aspects of health care relevant to health care professionals, members of clinical ethics committees, medical ethics professionals, researchers and bioscientists, policy makers and patients. Subscribers to the Journal of Medical Ethics also receive Medical Humanities journal at no extra cost. JME is the official journal of the Institute of Medical Ethics.
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