Soyang Ella Kim, Reem Farwana, Alfonso Vasquez-Perez
{"title":"复发性DMEK失败与眼内tutopplasty有关。","authors":"Soyang Ella Kim, Reem Farwana, Alfonso Vasquez-Perez","doi":"10.1097/ICO.0000000000003994","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>We report a unique case of recurrent Descemet membrane endothelial keratoplasty (DMEK) failure in a 69-year-old man with a history of pseudophakic bullous keratopathy (PBK) secondary to glaucoma surgeries.</p><p><strong>Methods: </strong>This is a retrospective case report.</p><p><strong>Results: </strong>The initial PAUL glaucoma implant was relocated to the sulcus, and the original sclerostomy was plugged with Tutoplast. The patient subsequently developed PBK and underwent 3 DMEK procedures, each resulting in immediate failure, beginning inferiorly despite uneventful surgery. Subsequent assessment revealed that the Tutoplast was protruding into the anterior chamber and contacting the inferior cornea. This contact was associated with endothelial dysfunction in the transplanted DMEK, leading to complete failure. After removal of the Tutoplast and scleral patch, the patient underwent a fourth DMEK procedure, which has been successful and remains well-functioning after 9 months.</p><p><strong>Conclusions: </strong>This is the first published case highlighting endothelial failure associated with Tutoplast and underscores the importance of thorough preoperative assessment.</p>","PeriodicalId":10710,"journal":{"name":"Cornea","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Recurrent DMEK Failures Related to Intraocular Tutoplast.\",\"authors\":\"Soyang Ella Kim, Reem Farwana, Alfonso Vasquez-Perez\",\"doi\":\"10.1097/ICO.0000000000003994\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>We report a unique case of recurrent Descemet membrane endothelial keratoplasty (DMEK) failure in a 69-year-old man with a history of pseudophakic bullous keratopathy (PBK) secondary to glaucoma surgeries.</p><p><strong>Methods: </strong>This is a retrospective case report.</p><p><strong>Results: </strong>The initial PAUL glaucoma implant was relocated to the sulcus, and the original sclerostomy was plugged with Tutoplast. The patient subsequently developed PBK and underwent 3 DMEK procedures, each resulting in immediate failure, beginning inferiorly despite uneventful surgery. Subsequent assessment revealed that the Tutoplast was protruding into the anterior chamber and contacting the inferior cornea. This contact was associated with endothelial dysfunction in the transplanted DMEK, leading to complete failure. After removal of the Tutoplast and scleral patch, the patient underwent a fourth DMEK procedure, which has been successful and remains well-functioning after 9 months.</p><p><strong>Conclusions: </strong>This is the first published case highlighting endothelial failure associated with Tutoplast and underscores the importance of thorough preoperative assessment.</p>\",\"PeriodicalId\":10710,\"journal\":{\"name\":\"Cornea\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cornea\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/ICO.0000000000003994\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cornea","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/ICO.0000000000003994","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Recurrent DMEK Failures Related to Intraocular Tutoplast.
Purpose: We report a unique case of recurrent Descemet membrane endothelial keratoplasty (DMEK) failure in a 69-year-old man with a history of pseudophakic bullous keratopathy (PBK) secondary to glaucoma surgeries.
Methods: This is a retrospective case report.
Results: The initial PAUL glaucoma implant was relocated to the sulcus, and the original sclerostomy was plugged with Tutoplast. The patient subsequently developed PBK and underwent 3 DMEK procedures, each resulting in immediate failure, beginning inferiorly despite uneventful surgery. Subsequent assessment revealed that the Tutoplast was protruding into the anterior chamber and contacting the inferior cornea. This contact was associated with endothelial dysfunction in the transplanted DMEK, leading to complete failure. After removal of the Tutoplast and scleral patch, the patient underwent a fourth DMEK procedure, which has been successful and remains well-functioning after 9 months.
Conclusions: This is the first published case highlighting endothelial failure associated with Tutoplast and underscores the importance of thorough preoperative assessment.
期刊介绍：
For corneal specialists and for all general ophthalmologists with an interest in this exciting subspecialty, Cornea brings together the latest clinical and basic research on the cornea and the anterior segment of the eye. Each volume is peer-reviewed by Cornea''s board of world-renowned experts and fully indexed in archival format. Your subscription brings you the latest developments in your field and a growing library of valuable professional references.
Sponsored by The Cornea Society which was founded as the Castroviejo Cornea Society in 1975.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
