酒精使用障碍与肺炎:易感性和严重程度

IF 2.7
Asad J Gandapur, Todd A Wyatt
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引用次数: 0

摘要

酒精使用障碍(AUD)是一个重大的公共卫生问题,产生深远的生理影响。AUD是一个未被充分认识的关键风险因素,但临床医生在处理这一弱势群体的肺炎时需要意识到并筛查预防和治疗策略。本研究通过检查肺部感染风险升高和疾病严重程度加剧来调查AUD与肺炎之间的联系。涵盖领域:现有的流行病学数据显示,AUD患者社区获得性和医院获得性肺炎的发病率均有所上升。这篇综述根据目前的研究结果,探讨了AUD的详细机制。为此,我们在1785年至2025年的PubMed中进行了全面的文献检索。“公开证据”也被用作搜索引擎,用于查找针对特定感兴趣问题的特定论文。专家意见:这些研究表明,饮酒通过各种机制使人们更容易受到感染。酒精相关合并症加剧肺炎结局,导致住院率升高、重症监护病房(ICU)入院和患者死亡。这篇综述强调需要结合治疗药物使用障碍和预防感染风险的措施,以改善患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Alcohol use disorders and pneumonia: susceptibility and severity.

Introduction: Alcohol use disorder (AUD) represents a major public health issue that produces far-reaching physiological effects. AUD is an underappreciated, yet critical risk factor clinicians need to be aware of and screen for to integrate preventive and therapeutic strategies when dealing with pneumonia in this vulnerable population. This research paper investigates the link between AUD and pneumonia by examining both the elevated risk of lung infection and the intensified disease severity.

Areas covered: The available epidemiological data show that people with AUD experience elevated rates of both community-acquired and hospital-acquired pneumonia. This review examines the detailed mechanisms of AUD as suggested by current research findings. For this purpose, a comprehensive literature search was conducted in PubMed between 1785 and 2025. Open Evidence was also used as a search engine to look for specific papers addressing a specific question of interest.

Expert opinion: These studies indicate that alcohol consumption makes people more prone to infections through various mechanisms. Alcohol-related comorbidities exacerbate pneumonia outcomes, resulting in elevated hospitalization rates, intensive care unit (ICU) admissions, and patient deaths. This review emphasizes the need for combined healthcare strategies that treat substance use disorders together with measures to prevent infection risks to improve patient outcomes.

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