Francisco Laxague, Drosa Zabihi-Pour, Claudia C Correa Roa, Josefina Principe, Adrian Mendez, Juan Manuel Fernandez Vila, Anthony C Nichols
{"title":"经口机器人手术(TORS)与开放手术治疗复发性口咽鳞状细胞癌:系统回顾和荟萃分析。","authors":"Francisco Laxague, Drosa Zabihi-Pour, Claudia C Correa Roa, Josefina Principe, Adrian Mendez, Juan Manuel Fernandez Vila, Anthony C Nichols","doi":"10.1002/hed.70042","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Salvage surgery (SS) is one of the best treatment options for recurrent oropharyngeal squamous cell carcinoma (OPSCC) after prior definitive radiation.</p><p><strong>Methods: </strong>A Medline literature search of articles on open (OSS) and transoral robotic surgery (TORS) for the treatment of recurrent OPSCC was performed. Surgical, functional, and oncological outcomes were analyzed and compared.</p><p><strong>Results: </strong>A total of 18 studies including 567 (66.2%) patients undergoing OSS and 290 (33.8%) undergoing TORS were included. Patients undergoing TORS vs. OSS had early T- and N-classification tumors, p < 0.01, respectively. OSS patients had higher rates of feeding tube and tracheostomy dependence compared with TORS (p < 0.01). The mean 2-year overall survival in patients undergoing TORS was 68.5% versus 45.9% in the OSS group, p = 0.03.</p><p><strong>Conclusion: </strong>Patients undergoing TORS had smaller tumors and less advanced nodal disease. Furthermore, they developed less postoperative feeding tube and tracheostomy dependency, and had better 2-year overall survival than patients undergoing OSS.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transoral Robotic Surgery (TORS) Versus Open Surgery for Recurrent Oropharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.\",\"authors\":\"Francisco Laxague, Drosa Zabihi-Pour, Claudia C Correa Roa, Josefina Principe, Adrian Mendez, Juan Manuel Fernandez Vila, Anthony C Nichols\",\"doi\":\"10.1002/hed.70042\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Salvage surgery (SS) is one of the best treatment options for recurrent oropharyngeal squamous cell carcinoma (OPSCC) after prior definitive radiation.</p><p><strong>Methods: </strong>A Medline literature search of articles on open (OSS) and transoral robotic surgery (TORS) for the treatment of recurrent OPSCC was performed. Surgical, functional, and oncological outcomes were analyzed and compared.</p><p><strong>Results: </strong>A total of 18 studies including 567 (66.2%) patients undergoing OSS and 290 (33.8%) undergoing TORS were included. Patients undergoing TORS vs. OSS had early T- and N-classification tumors, p < 0.01, respectively. OSS patients had higher rates of feeding tube and tracheostomy dependence compared with TORS (p < 0.01). The mean 2-year overall survival in patients undergoing TORS was 68.5% versus 45.9% in the OSS group, p = 0.03.</p><p><strong>Conclusion: </strong>Patients undergoing TORS had smaller tumors and less advanced nodal disease. Furthermore, they developed less postoperative feeding tube and tracheostomy dependency, and had better 2-year overall survival than patients undergoing OSS.</p>\",\"PeriodicalId\":55072,\"journal\":{\"name\":\"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/hed.70042\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/hed.70042","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
Transoral Robotic Surgery (TORS) Versus Open Surgery for Recurrent Oropharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.
Background: Salvage surgery (SS) is one of the best treatment options for recurrent oropharyngeal squamous cell carcinoma (OPSCC) after prior definitive radiation.
Methods: A Medline literature search of articles on open (OSS) and transoral robotic surgery (TORS) for the treatment of recurrent OPSCC was performed. Surgical, functional, and oncological outcomes were analyzed and compared.
Results: A total of 18 studies including 567 (66.2%) patients undergoing OSS and 290 (33.8%) undergoing TORS were included. Patients undergoing TORS vs. OSS had early T- and N-classification tumors, p < 0.01, respectively. OSS patients had higher rates of feeding tube and tracheostomy dependence compared with TORS (p < 0.01). The mean 2-year overall survival in patients undergoing TORS was 68.5% versus 45.9% in the OSS group, p = 0.03.
Conclusion: Patients undergoing TORS had smaller tumors and less advanced nodal disease. Furthermore, they developed less postoperative feeding tube and tracheostomy dependency, and had better 2-year overall survival than patients undergoing OSS.
期刊介绍:
Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.