制造不含奶牛的酪蛋白和酪蛋白胶束。

IF 14.9 1区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Trends in biotechnology Pub Date : 2025-10-01 Epub Date: 2025-09-08 DOI:10.1016/j.tibtech.2025.08.016

Carl Holt

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引用次数: 0

摘要

酪蛋白精确发酵的关键步骤是正确磷酸化，以产生一个或多个短线性序列基序（slms），其中包含三个或更多磷酸化的丝氨酸残基。Balasubramanian等人的研究表明，两种细菌磷酸激酶是哺乳动物高尔基磷酸激酶和酪蛋白激酶- ii的有希望的替代品，这使我们向这一目标迈进了一步。

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Making cow-free caseins and casein micelles.

A key step in the precision fermentation of casein proteins is correct phosphorylation to generate one or more short linear sequence motifs (SLiMs) containing three or more phosphorylated seryl residues. The work of Balasubramanian et al. takes us a step closer to that goal by showing that two bacterial phosphokinases are promising alternatives to the mammalian Golgi phosphokinases and casein kinase-II.

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来源期刊

Trends in biotechnology 工程技术-生物工程与应用微生物

CiteScore

28.60

自引率

1.20%

发文量

198

审稿时长

1 months

期刊介绍： Trends in Biotechnology publishes reviews and perspectives on the applied biological sciences, focusing on useful science applied to, derived from, or inspired by living systems. The major themes that TIBTECH is interested in include: Bioprocessing (biochemical engineering, applied enzymology, industrial biotechnology, biofuels, metabolic engineering) Omics (genome editing, single-cell technologies, bioinformatics, synthetic biology) Materials and devices (bionanotechnology, biomaterials, diagnostics/imaging/detection, soft robotics, biosensors/bioelectronics) Therapeutics (biofabrication, stem cells, tissue engineering and regenerative medicine, antibodies and other protein drugs, drug delivery) Agroenvironment (environmental engineering, bioremediation, genetically modified crops, sustainable development).