{"title":"高频重复经颅磁刺激结合康复治疗脊髓损伤患者的有效性：系统综述。","authors":"Rudraksh Banga, Kavin Devani, Kanwal Preet Kochhar, Suman Jain","doi":"10.1080/01616412.2025.2558860","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Spinal Cord Injury (SCI) leads to partial or complete sensorimotor loss because of the spinal lesions caused either by trauma or any pathological conditions. Rehabilitation, one of the therapeutic methods, is considered to be a significant part of therapy supporting patients with spinal cord injury. Newer methods are being incorporated, such as repetitive Transcranial Magnetic Stimulation (rTMS), a Non-Invasive Brain Stimulation (NIBS) technique to induce changes in the residual neuronal pathways, facilitating cortical excitability and neuroplasticity.</p><p><strong>Study design: </strong>PRISMA-guided systematic review.</p><p><strong>Objective: </strong>To comprehend the therapeutic efficacy of rTMS combined with rehabilitation in SCI patients by evaluating the results reported in previous studies.</p><p><strong>Methodology: </strong>An online electronic search was executed on the scientific databases, PUBMED, COCHRANE LIBRARY, and SCOPUS using the keywords: 'Spinal Cord Injury (SCI),' 'repetitive Transcranial Magnetic Stimulation (rTMS),' and 'rehabilitation' and articles published in the English language between the years 2010 to 2024 were screened and extracted based on the eligibility criteria according to PICOS framework.</p><p><strong>Results: </strong>Four full-text articles were selected and analysed. Following HF-rTMS and neuro-rehabilitation, significant upper and lower extremity functional gains marked by UEMS & LEMS and a reduction in lower limb spasticity were reported by MAS scores in active SCI groups.</p><p><strong>Conclusion: </strong>To modulate corticospinal tract fiber excitability and reduce spasticity in patients with SCI, HF-rTMS shows promising therapeutic effects if combined with a rehabilitation program.</p><p><strong>Prospero id: </strong>CRD420251028333.</p>","PeriodicalId":19131,"journal":{"name":"Neurological Research","volume":" ","pages":"1-11"},"PeriodicalIF":1.5000,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effectiveness of high-frequency repetitive transcranial magnetic stimulation coupled with rehabilitation in patients with spinal cord injury: a systematic review.\",\"authors\":\"Rudraksh Banga, Kavin Devani, Kanwal Preet Kochhar, Suman Jain\",\"doi\":\"10.1080/01616412.2025.2558860\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Spinal Cord Injury (SCI) leads to partial or complete sensorimotor loss because of the spinal lesions caused either by trauma or any pathological conditions. Rehabilitation, one of the therapeutic methods, is considered to be a significant part of therapy supporting patients with spinal cord injury. Newer methods are being incorporated, such as repetitive Transcranial Magnetic Stimulation (rTMS), a Non-Invasive Brain Stimulation (NIBS) technique to induce changes in the residual neuronal pathways, facilitating cortical excitability and neuroplasticity.</p><p><strong>Study design: </strong>PRISMA-guided systematic review.</p><p><strong>Objective: </strong>To comprehend the therapeutic efficacy of rTMS combined with rehabilitation in SCI patients by evaluating the results reported in previous studies.</p><p><strong>Methodology: </strong>An online electronic search was executed on the scientific databases, PUBMED, COCHRANE LIBRARY, and SCOPUS using the keywords: 'Spinal Cord Injury (SCI),' 'repetitive Transcranial Magnetic Stimulation (rTMS),' and 'rehabilitation' and articles published in the English language between the years 2010 to 2024 were screened and extracted based on the eligibility criteria according to PICOS framework.</p><p><strong>Results: </strong>Four full-text articles were selected and analysed. Following HF-rTMS and neuro-rehabilitation, significant upper and lower extremity functional gains marked by UEMS & LEMS and a reduction in lower limb spasticity were reported by MAS scores in active SCI groups.</p><p><strong>Conclusion: </strong>To modulate corticospinal tract fiber excitability and reduce spasticity in patients with SCI, HF-rTMS shows promising therapeutic effects if combined with a rehabilitation program.</p><p><strong>Prospero id: </strong>CRD420251028333.</p>\",\"PeriodicalId\":19131,\"journal\":{\"name\":\"Neurological Research\",\"volume\":\" \",\"pages\":\"1-11\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-09-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurological Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/01616412.2025.2558860\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurological Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/01616412.2025.2558860","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Effectiveness of high-frequency repetitive transcranial magnetic stimulation coupled with rehabilitation in patients with spinal cord injury: a systematic review.
Background: Spinal Cord Injury (SCI) leads to partial or complete sensorimotor loss because of the spinal lesions caused either by trauma or any pathological conditions. Rehabilitation, one of the therapeutic methods, is considered to be a significant part of therapy supporting patients with spinal cord injury. Newer methods are being incorporated, such as repetitive Transcranial Magnetic Stimulation (rTMS), a Non-Invasive Brain Stimulation (NIBS) technique to induce changes in the residual neuronal pathways, facilitating cortical excitability and neuroplasticity.
Study design: PRISMA-guided systematic review.
Objective: To comprehend the therapeutic efficacy of rTMS combined with rehabilitation in SCI patients by evaluating the results reported in previous studies.
Methodology: An online electronic search was executed on the scientific databases, PUBMED, COCHRANE LIBRARY, and SCOPUS using the keywords: 'Spinal Cord Injury (SCI),' 'repetitive Transcranial Magnetic Stimulation (rTMS),' and 'rehabilitation' and articles published in the English language between the years 2010 to 2024 were screened and extracted based on the eligibility criteria according to PICOS framework.
Results: Four full-text articles were selected and analysed. Following HF-rTMS and neuro-rehabilitation, significant upper and lower extremity functional gains marked by UEMS & LEMS and a reduction in lower limb spasticity were reported by MAS scores in active SCI groups.
Conclusion: To modulate corticospinal tract fiber excitability and reduce spasticity in patients with SCI, HF-rTMS shows promising therapeutic effects if combined with a rehabilitation program.
期刊介绍：
Neurological Research is an international, peer-reviewed journal for reporting both basic and clinical research in the fields of neurosurgery, neurology, neuroengineering and neurosciences. It provides a medium for those who recognize the wider implications of their work and who wish to be informed of the relevant experience of others in related and more distant fields.
The scope of the journal includes:
•Stem cell applications
•Molecular neuroscience
•Neuropharmacology
•Neuroradiology
•Neurochemistry
•Biomathematical models
•Endovascular neurosurgery
•Innovation in neurosurgery.
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