儿童原发性胰腺神经母细胞瘤的诊断和治疗：罕见部位常见恶性肿瘤病例报告。

IF 0.8 4区医学 Q4 HEMATOLOGY

Journal of Pediatric Hematology/Oncology Pub Date : 2025-09-03 DOI:10.1097/MPH.0000000000003118

Dipesh Dave, Maharshi Trivedi, Chinmay Doctor, Harsha Panchal, Biren Parikh, Ritesh Suthar

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引用次数: 0

摘要

小儿胰腺神经母细胞瘤是一种罕见的儿童癌症，在文献中只有有限的病例。我们报告一个病例4岁女孩诊断为高风险胰腺神经母细胞瘤。女孩接受诱导化疗，随后进行自体干细胞移植和13-顺式维甲酸维持治疗。由于诱导后的肿块很小，肿瘤的位置和预期的毒性，手术和放疗是不可行的。这名女孩成功完成了治疗，自体干细胞移植1年半后没有任何疾病迹象。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Diagnosis and Management of a Child With Primary Pancreatic Neuroblastoma: Case Report of a Common Malignancy at a Rare Site.

Pediatric pancreatic neuroblastoma is a rare cancer in children, with only limited cases available in the literature. We report a case of a 4-year-old girl diagnosed with high-risk pancreatic neuroblastoma. The girl was treated with induction chemotherapy followed by autologous stem cell transplant and maintenance with 13-cis-retinoic acid. Surgery and radiotherapy were not feasible due to the very small size of the mass postinduction, the location of the tumor, and the expected toxicities. The girl completed treatment successfully and is now 1 and a half years postautologous stem cell transplant without any evidence of disease.

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来源期刊

Journal of Pediatric Hematology/Oncology 医学-小儿科

CiteScore

1.90

自引率

8.30%

发文量

415

审稿时长

2.5 months

期刊介绍： Journal of Pediatric Hematology/Oncology (JPHO) reports on major advances in the diagnosis and treatment of cancer and blood diseases in children. The journal publishes original research, commentaries, historical insights, and clinical and laboratory observations.