埃及Beni-Suef省甲状腺结节良恶性鉴别的危险因素及超声特征评估

IF 3.3 3区 医学 Q3 ENDOCRINOLOGY & METABOLISM
Ahmed Moheyeldien Hamed, Khaled Elsayed Elhadidy, Mahmoud Farid Kamel, Ahmed Sayed Abd El Basset, Ahmed Saad Ahmed, Saeed M Shaaban, Nadia Ahmed Abd El-Moeze, Hazem Samy Matar
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引用次数: 0

摘要

背景:甲状腺结节(TNs)是一种常见的良性结节。准确区分良恶性结节对正确治疗至关重要。本研究旨在利用超声检查TNs,识别可能的危险因素,以提高患者的预后和诊断准确性。方法:本研究纳入了128例甲状腺功能正常的接受甲状腺切除术的参与者,根据组织病理学结果分为两组(良性和恶性)。收集了年龄、性别、甲状腺癌家族史和辐射暴露的数据。超声(US)评估结节数量、大小、血管状况和TIRAD评分。US淋巴结状态也被评估。对良、恶性结节进行统计学分析比较。结果:良性组和恶性组在年龄、性别、家族史、辐射暴露等方面无显著差异。结论:本研究显示,甲状腺良恶性肿瘤组间性别、年龄、甲状腺癌家族史、辐射暴露史无显著差异。较高的TIRAD评分和低回声结节在恶性结节中更为常见。良性结节边缘更光滑,更大,更有可能出现超/等回声。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Assessment of risk factors and ultrasonographic characteristics for the differentiation between malignant and benign thyroid nodules in Beni-Suef governorate, Egypt.

Assessment of risk factors and ultrasonographic characteristics for the differentiation between malignant and benign thyroid nodules in Beni-Suef governorate, Egypt.

Background: Thyroid nodules (TNs) are frequent and often benign. Accurately differentiating between benign and malignant nodules is crucial for proper management. This research aims to use ultrasonography to examine TNs and identify possible risk factors in order to improve patient outcomes and diagnostic accuracy.

Methods: The study included 128 euthyroid participants who underwent thyroidectomy, splitted into two groups (benign and malignant) regarding the histopathological outcomes. Data on age, sex, family history of thyroid cancer and radiation exposure were collected. Ultrasound (US) was used to assess nodule number, size, vascularity and TIRAD scores. US Lymph node status was also evaluated. Statistical analysis compared benign and malignant nodules.

Results: No significant differences were found between benign and malignant groups regarding age, sex, family history, and radiation exposure. Significant differences were observed in nodule size (p < 0.05), echogenicity (p < 0.001), and margins (p < 0.05), with larger, hyper/isoechoic, and smooth-margined nodules more common in the benign group. TIRAD scores (p < 0.001) and lymph node status (p < 0.001) also differed significantly, with benign cases showing TR3 scores and non-suspicious lymph nodes, while malignant cases had more TR4 scores and suspicious lymph nodes. Additionally, malignant nodules were significantly more hypoechoic (p < 0.001). Most benign cases were nodular colloid hyperplasia, followed by follicular adenoma and thyroiditis. Most malignant cases were Papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC). PTC was associated with younger age (p = 0.006), smaller nodule size (p = 0.04), and hypoechoic nodules (p = 0.04).

Conclusion: Sex, age, family history of thyroid cancer, and radiation exposure history did not significantly vary between groups with benign and malignant thyroid tumors, according to the research. Higher TIRAD scores and hypoechoic nodules were more common in malignant nodules. Benign nodules had smoother margins, were bigger, and were more likely to be hyper/isoechoic.

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来源期刊
BMC Endocrine Disorders
BMC Endocrine Disorders ENDOCRINOLOGY & METABOLISM-
CiteScore
4.40
自引率
0.00%
发文量
280
审稿时长
>12 weeks
期刊介绍: BMC Endocrine Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of endocrine disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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