Copper(II) Complexes with 1-[Anilino(2-methoxyanilino)]-3-acetoxy(methoxy)propane-2-thiol and Their Application

The reactions of copper(II) with 2-mercapto-3-(phenylamino)propyl acetate (AAPT) and 1-methoxy-3-[(2-methoxyphenyl)amino]propane-2-thiol (MMPT) was studied by the extraction-photometric method. The ligands were characterized with IR and NMR spectroscopy. The influence of aqueous phase pH on the formation of CuL₂ complexes and thermal decomposition were studied. Chloroform was chosen as the best extractant. A single extraction with chloroform extracted 98.6–99.3% of Cu(II). The yield of CuL₂ was maximum at c_L = 0.008 M and did not decompose for 24 hours or more than 45 days after extraction. Maximum light absorption is achieved within 10 minutes. Phase volume ratios of 5:5–115:5 did not affect the recovery. The optimum acidity is in the range of pH_opt = 0.3–6.7 (pH_form = 2.1–4.7). The molar absorption coefficients are ε_480–490 = (4.21–4.26) × 10⁴. Compliance with the fundamental law of light absorption is achieved at c_Cu(II) = 0.16–18 μg/mL. The ratio of components in the complex is 1:2. The developed extraction-photometric method was applied to determine copper in pharmaceutical and plant samples.