尿素连续流动甘油解制碳酸甘油：操作压力的关键作用

IF 3.9 3区工程技术 Q2 ENGINEERING, CHEMICAL

Industrial & Engineering Chemistry Research Pub Date : 2025-09-10 DOI:10.1021/acs.iecr.5c02554

Andrea Severini, , , Biagio Anderlini, , , Antonio Lezza, , , Marianna Burello, , , Nicola Porcelli, , , Marco Mazzali, , , Veronica D’Eusanio, , , Mirco Rivi, , , Claudio Fontanesi*, , and , Fabrizio Roncaglia*,

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引用次数: 0

摘要

对甘油与尿素羰基化反应进行了理论与实验相结合的研究，确定了低操作压力是工艺优化的关键参数。基于这些见解，开发了一种改进的多道连续流系统，可以提高无溶剂合成碳酸甘油（GC）的效率。优化后的工艺实现了约130克/天的生产率，提供高纯度（>95%），分离收率为80%，从而证明了该方法可持续气相色谱生产的可行性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Continuous-Flow Glycerolysis of Urea to Glycerol Carbonate: The Critical Role of Operating Pressure

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Continuous-Flow Glycerolysis of Urea to Glycerol Carbonate: The Critical Role of Operating Pressure

A combined theoretical and experimental study on the carbonylation of glycerol with urea has identified low operating pressure as a key parameter for process optimization. Based on these insights, an improved multiple-pass continuous-flow system was developed, enabling the solvent-free synthesis of glycerol carbonate (GC) with enhanced efficiency. The optimized process achieved a productivity of ∼130 g/day, delivering high purity (>95%), and an isolated yield of 80%, thereby demonstrating the viability of this approach for sustainable GC production.

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来源期刊

Industrial & Engineering Chemistry Research 工程技术-工程：化工

CiteScore

7.40

自引率

7.10%

发文量

1467

审稿时长

2.8 months

期刊介绍： ndustrial & Engineering Chemistry, with variations in title and format, has been published since 1909 by the American Chemical Society. Industrial & Engineering Chemistry Research is a weekly publication that reports industrial and academic research in the broad fields of applied chemistry and chemical engineering with special focus on fundamentals, processes, and products.