卡巴唑-丹酚缀合物用于约会油菜药物的潜在指纹可视化和现场检测

IF 3.3 3区 化学 Q2 CHEMISTRY, ANALYTICAL
Analyst Pub Date : 2025-09-10 DOI:10.1039/d5an00675a
Meghana Sharma, Shagun, Anish Chhillar, Amit Jaiswal, Abhimanew Dhir
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引用次数: 0

摘要

设计并合成了一种亚胺连接丹酰咔唑分子体系DASH。该系统(DASH)经过合理设计,除了潜在指纹检测外,还可作为检测约会强奸药物(即γ -丁内酯(GBL)和γ -戊内酯(GVL))的合适模板。强奸、毒品和潜在指纹检测都是毒品犯罪法医分析的重要内容。在许多报告中,这两种应用程序都得到了很好的独立探索。然而,目前还没有报道双重应用的荧光系统。本研究报道了分子系统DASH的双重应用,它同时展示了固体状态下枣油菜药物的现场检测和不同表面上的潜在指纹检测。利用细胞活力试验和DNA损伤分析证实了DASH的生物相容性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Carbazole–dansyl conjugate for latent fingerprint visualization and on-site detection of date rape drugs

Carbazole–dansyl conjugate for latent fingerprint visualization and on-site detection of date rape drugs
An imino-linked dansyl–carbazole molecular system, DASH, is designed and synthesized. This system (DASH) is rationalized in such a way that it works as a suitable template for the detection of date rape drugs, i.e. gamma-butyrolactone (GBL) and gamma-valerolactone (GVL), in addition to latent fingerprint detection. Both rape drug and latent fingerprint detection are important aspects of drug abuse-related crimes in forensic analysis. There are many reports where both applications have been independently well explored. However, there is no fluorescent system so far that has been reported for dual application. The present study reports the dual application of the molecular system DASH, which simultaneously demonstrates on-site detection of date rape drugs in the solid state as well as latent fingerprint detection on different surfaces. The biocompatibility of DASH is proved utilizing cell viability assay and DNA damage analysis.
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来源期刊
Analyst
Analyst 化学-分析化学
CiteScore
7.80
自引率
4.80%
发文量
636
审稿时长
1.9 months
期刊介绍: "Analyst" journal is the home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences.
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