纳米孔也会给蛋白质排序吗？］

IF 0.4 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

M S-medecine Sciences Pub Date : 2025-08-01 Epub Date: 2025-09-08 DOI:10.1051/medsci/2025111

Bertrand Jordan

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引用次数: 0

摘要

利用纳米孔进行DNA测序现在已经很成熟了。这种方法可以扩展到蛋白质吗？有许多困难，但许多小组的工作已经为大多数困难提供了原理证明解决方案。进一步的进展确实可能导致一种可行的蛋白质测序方法，这种方法将在研究和临床中有许多应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Will nanopores also sequence proteins ?]

DNA sequencing using nanopores is now well established. Could the approach be extended to proteins ? There are a number of difficulties but work by many groups has shown proof-of-principle solutions for most of them. Further progress could indeed lead to a workable protein sequencing approach that would have many applications in research and in the clinic.

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来源期刊

M S-medecine Sciences 医学-医学：研究与实验

CiteScore

0.80

自引率

14.30%

发文量

182

审稿时长

4-8 weeks

期刊介绍： m/s offers high-quality review articles in French, covering all areas of biomedical and health research, in a monthly magazine format (10 issues / year). m/s is read by the whole French-speaking community, in France but also in Belgium, Switzerland, Canada, Morocco, Algeria, Tunisia etc. m/s is not a primary publication, and thus will not consider unpublished data. Most articles are invited by the Editors, but spontaneous proposals are welcomed. Each issue combines news and views on the most recent scientific publications, as well as broadly accessible and updated review articles on a specific topic, and essays on science and society, history of science, public health, or reactions to published articles. Each year, m/s also publishes one or two thematic issues focused on a research topic of high interest. All review articles and essays are peer-reviewed.