银屑病患者肺功能检查异常

IF 2.7 3区医学 Q2 DERMATOLOGY

Dermatology Pub Date : 2025-09-08 DOI:10.1159/000548175

Mateusz Mleczko, Maciej Zakrzewski, Agnieszka Gerkowicz, Jerzy Mosiewicz, Dorota Krasowska

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引用次数: 0

摘要

银屑病与肺部疾病相关，但目前还没有关于银屑病患者全肺功能测试（PFTs）的研究。本研究的目的是比较银屑病患者和对照组的肺功能测量值。方法：68例银屑病患者和68例符合纳入标准的性别和年龄匹配的对照组。对所有研究参与者进行肺功能测试、体体积脉搏图和DLCO测试。结果：银屑病患者FEV1/FVC均值明显低于对照组（98±6.6∶100.3±3.2,p < 0.05）。在亚组分析中，银屑病患者非吸烟和非肥胖组FEV1/FVC比值显著低于对照组（分别为98.2±5∶100.6±2.7,p < 0.05和98±6.8∶100±3.1,p < 0.05）。两组患者体体积脉搏图及DLCO测试参数差异无统计学意义。结论：银屑病患者的平均FEV1/FVC比低于对照组。FEV1/FVC比值与牛皮癣的存在独立相关。

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Abnormalities in Pulmonary Function Tests in Patients with Psoriasis.

Introduction: Psoriasis is associated with lung diseases, but there have been no studies on full pulmonary function tests (PFTs) in patients with psoriasis. The aim of this study was to compare pulmonary function measurements in patients with psoriasis and controls.

Methods: Sixty-eight patients with psoriasis and sixty-eight sex- and age-matched controls fulfilling the inclusion criteria were included in this study. Spirometric pulmonary function testing, body plethysmography, and DLCO testing were performed on all study participants.

Results: The mean FEV1/FVC ratio was significantly lower in the psoriasis patients than in the controls (98 ± 6.6 vs. 100.3 ± 3.2, p < 0.05). In the subgroup analysis, the FEV1/FVC ratio in non-smoking and non-obese subjects was significantly lower in psoriasis patients than controls (98.2 ± 5 vs. 100.6 ± 2.7; p < 0.05 and 98 ± 6.8 vs. 100 ± 3.1; p < 0.05, respectively). There was no statistically significant difference in body plethysmography or the DLCO test parameters between groups.

Conclusion: Psoriasis patients had a lower mean FEV1/FVC ratio compared to the control subjects. The FEV1/FVC ratio was independently associated with the presence of psoriasis.

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来源期刊

Dermatology 医学-皮肤病学

CiteScore

6.40

自引率

2.90%

发文量

审稿时长

1 months

期刊介绍： Published since 1893, ''Dermatology'' provides a worldwide survey of clinical and investigative dermatology. Original papers report clinical and laboratory findings. In order to inform readers of the implications of recent research, editorials and reviews prepared by invited, internationally recognized scientists are regularly featured. In addition to original papers, the journal publishes rapid communications, short communications, and letters to ''Dermatology''. ''Dermatology'' answers the complete information needs of practitioners concerned with progress in research related to skin, clinical dermatology and therapy. The journal enjoys a high scientific reputation with a continually increasing impact factor and an equally high circulation.