L N Wang, H X Yang, M H Dong, P P Liu, H Y Zhao, J Li
{"title":"ABO血型与酒精性肝病的相关性","authors":"L N Wang, H X Yang, M H Dong, P P Liu, H Y Zhao, J Li","doi":"10.7754/Clin.Lab.2025.250202","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Since the discovery of ABO blood groups, there has been mounting evidence of the association between blood groups and diseases. However, so far, there is rarely available research about the potential role of ABO blood groups in alcohol liver disease (ALD). This study's aim was to investigate the relationship between ABO blood groups and the development of ALD in Qingdao, China.</p><p><strong>Methods: </strong>This experiment carried out a retrospective study enrolling 252 ALD patients as the case group and 373 healthy subjects as the control group. ABO blood group distribution was analyzed using the chi-squared test and logistic regression analysis.</p><p><strong>Results: </strong>Results showed that the distribution of ABO blood types between the two groups was significantly different (χ2 = 22.350, p < 0.05). Blood type O was less frequently observed [odds ratio (OR), 0.498; confidence interval (CI), 0.329 - 0.755; p < 0.05], while blood type AB was more frequently observed in the case group (OR, 2.550; CI, 1.589 - 4.092; p < 0.05).</p><p><strong>Conclusions: </strong>The findings indicate that populations with blood type AB might be more prone to ALD, whereas those with blood type O might be less susceptible to ALD, which will help in the risk stratification in ALD control.</p>","PeriodicalId":10384,"journal":{"name":"Clinical laboratory","volume":"71 9","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Correlation between ABO Blood Types and Alcoholic Liver Disease.\",\"authors\":\"L N Wang, H X Yang, M H Dong, P P Liu, H Y Zhao, J Li\",\"doi\":\"10.7754/Clin.Lab.2025.250202\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Since the discovery of ABO blood groups, there has been mounting evidence of the association between blood groups and diseases. However, so far, there is rarely available research about the potential role of ABO blood groups in alcohol liver disease (ALD). This study's aim was to investigate the relationship between ABO blood groups and the development of ALD in Qingdao, China.</p><p><strong>Methods: </strong>This experiment carried out a retrospective study enrolling 252 ALD patients as the case group and 373 healthy subjects as the control group. ABO blood group distribution was analyzed using the chi-squared test and logistic regression analysis.</p><p><strong>Results: </strong>Results showed that the distribution of ABO blood types between the two groups was significantly different (χ2 = 22.350, p < 0.05). Blood type O was less frequently observed [odds ratio (OR), 0.498; confidence interval (CI), 0.329 - 0.755; p < 0.05], while blood type AB was more frequently observed in the case group (OR, 2.550; CI, 1.589 - 4.092; p < 0.05).</p><p><strong>Conclusions: </strong>The findings indicate that populations with blood type AB might be more prone to ALD, whereas those with blood type O might be less susceptible to ALD, which will help in the risk stratification in ALD control.</p>\",\"PeriodicalId\":10384,\"journal\":{\"name\":\"Clinical laboratory\",\"volume\":\"71 9\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical laboratory\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.7754/Clin.Lab.2025.250202\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICAL LABORATORY TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical laboratory","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.7754/Clin.Lab.2025.250202","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
The Correlation between ABO Blood Types and Alcoholic Liver Disease.
Background: Since the discovery of ABO blood groups, there has been mounting evidence of the association between blood groups and diseases. However, so far, there is rarely available research about the potential role of ABO blood groups in alcohol liver disease (ALD). This study's aim was to investigate the relationship between ABO blood groups and the development of ALD in Qingdao, China.
Methods: This experiment carried out a retrospective study enrolling 252 ALD patients as the case group and 373 healthy subjects as the control group. ABO blood group distribution was analyzed using the chi-squared test and logistic regression analysis.
Results: Results showed that the distribution of ABO blood types between the two groups was significantly different (χ2 = 22.350, p < 0.05). Blood type O was less frequently observed [odds ratio (OR), 0.498; confidence interval (CI), 0.329 - 0.755; p < 0.05], while blood type AB was more frequently observed in the case group (OR, 2.550; CI, 1.589 - 4.092; p < 0.05).
Conclusions: The findings indicate that populations with blood type AB might be more prone to ALD, whereas those with blood type O might be less susceptible to ALD, which will help in the risk stratification in ALD control.
期刊介绍：
Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
