韩国患者抗核抗体试验中棒环型的临床研究。

IF 0.6 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Clinical laboratory Pub Date : 2025-09-01 DOI:10.7754/Clin.Lab.2024.241110

Ha-Eun Cho, Kyung Sun Park, Young Jin Kim, Tae Sung Park, Sun Young Cho

{"title":"韩国患者抗核抗体试验中棒环型的临床研究。","authors":"Ha-Eun Cho, Kyung Sun Park, Young Jin Kim, Tae Sung Park, Sun Young Cho","doi":"10.7754/Clin.Lab.2024.241110","DOIUrl":null,"url":null,"abstract":"Background: This study investigated the clinical significance of rods and rings (RR) immunofluorescence patterns in antinuclear antibody (ANA) testing by analyzing their clinical associations.Methods: A single-center retrospective analysis was conducted between January 2022 and December 2023, examining cases with RR patterns in ANA testing.Results: Among 40 cases (0.5%) showing RR patterns, 35% coincided with autoimmune diseases, 25% with infections, and 22.5% with other inflammatory conditions. In specimens with high-intensity fluorescence, 45% were as-sociated with infections, and 18% with autoimmune diseases. Elevated inflammatory markers were observed in 54.5% of cases with inflammatory manifestations.Conclusions: The findings suggest that RR patterns in ANA testing may serve as potential indicators of underlying inflammatory processes.","PeriodicalId":10384,"journal":{"name":"Clinical laboratory","volume":"71 9","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical Investigation of Rods and Rings Pattern in Anti-Nuclear Antibody Test in Korean Patients.\",\"authors\":\"Ha-Eun Cho, Kyung Sun Park, Young Jin Kim, Tae Sung Park, Sun Young Cho\",\"doi\":\"10.7754/Clin.Lab.2024.241110\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: This study investigated the clinical significance of rods and rings (RR) immunofluorescence patterns in antinuclear antibody (ANA) testing by analyzing their clinical associations.Methods: A single-center retrospective analysis was conducted between January 2022 and December 2023, examining cases with RR patterns in ANA testing.Results: Among 40 cases (0.5%) showing RR patterns, 35% coincided with autoimmune diseases, 25% with infections, and 22.5% with other inflammatory conditions. In specimens with high-intensity fluorescence, 45% were as-sociated with infections, and 18% with autoimmune diseases. Elevated inflammatory markers were observed in 54.5% of cases with inflammatory manifestations.Conclusions: The findings suggest that RR patterns in ANA testing may serve as potential indicators of underlying inflammatory processes.\",\"PeriodicalId\":10384,\"journal\":{\"name\":\"Clinical laboratory\",\"volume\":\"71 9\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical laboratory\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.7754/Clin.Lab.2024.241110\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICAL LABORATORY TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical laboratory","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.7754/Clin.Lab.2024.241110","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

背景：本研究通过分析抗核抗体（ANA）检测中棒环（rods and rings， RR）免疫荧光图谱的临床相关性，探讨其临床意义。方法：在2022年1月至2023年12月期间进行单中心回顾性分析，检查ANA检测中出现RR模式的病例。结果：在40例（0.5%）出现RR模式的病例中，35%与自身免疫性疾病合并，25%与感染合并，22.5%与其他炎症性疾病合并。在具有高强度荧光的标本中，45%与感染有关，18%与自身免疫性疾病有关。54.5%有炎症表现的患者炎症标志物升高。结论：研究结果表明，ANA检测中的RR模式可能作为潜在炎症过程的潜在指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Clinical Investigation of Rods and Rings Pattern in Anti-Nuclear Antibody Test in Korean Patients.

Background: This study investigated the clinical significance of rods and rings (RR) immunofluorescence patterns in antinuclear antibody (ANA) testing by analyzing their clinical associations.

Methods: A single-center retrospective analysis was conducted between January 2022 and December 2023, examining cases with RR patterns in ANA testing.

Results: Among 40 cases (0.5%) showing RR patterns, 35% coincided with autoimmune diseases, 25% with infections, and 22.5% with other inflammatory conditions. In specimens with high-intensity fluorescence, 45% were as-sociated with infections, and 18% with autoimmune diseases. Elevated inflammatory markers were observed in 54.5% of cases with inflammatory manifestations.

Conclusions: The findings suggest that RR patterns in ANA testing may serve as potential indicators of underlying inflammatory processes.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Clinical laboratory 医学-医学实验技术

CiteScore

1.50

自引率

0.00%

发文量

494

审稿时长

3 months

期刊介绍： Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.