{"title":"儿童尿中催产素水平与医院狗®。","authors":"A Risberg, A Larsson, U Bodén, A Edner","doi":"10.1186/s12906-025-05076-6","DOIUrl":null,"url":null,"abstract":"<p><p>There has been growing interest in animal-assisted therapy (AAT) in recent decades due to increasing reports indicating its health benefits for adult patients. These benefits are partly attributed to changes, usually increased levels of the neuropeptide oxytocin. AIM: To investigate changes in oxytocin levels in hospitalized children meeting a certified Hospital Dog<sup>®</sup>.</p><p><strong>Method: </strong>Urine samples were collected between 25/02/2016 and 24/05/2017 from 35 hospitalized children (3-17 years) before and after each participant had a session with the Hospital Dog<sup>®</sup>. Oxytocin levels were analysed with an acetylcholinesterase (AChE) competitive enzyme-linked immunosorbent assay (ELISA). Creatinine levels were measured to determine the subject's fluid intake and then divided by the hormonal concentration (uOT pg/ml).</p><p><strong>Results: </strong>The mean level of uOT was 186.0 ± 236.7 (51.5-1349.5) pg/ml before and 137.3 ± 121.5 (30.7-591.3) pg/ml after the dog session (p = 0.010).</p><p><strong>Conclusion: </strong>Decreased levels of uOT were recorded during the study in which hospitalized children met a Hospital Dog<sup>®</sup>. The decreased OT levels are potentially the result of the intense activity the subject experienced with the dog during the interaction.</p>","PeriodicalId":9128,"journal":{"name":"BMC Complementary Medicine and Therapies","volume":"25 1","pages":"327"},"PeriodicalIF":3.4000,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418696/pdf/","citationCount":"0","resultStr":"{\"title\":\"Urinary oxytocin levels in children meeting a Hospital Dog<sup>®</sup>.\",\"authors\":\"A Risberg, A Larsson, U Bodén, A Edner\",\"doi\":\"10.1186/s12906-025-05076-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>There has been growing interest in animal-assisted therapy (AAT) in recent decades due to increasing reports indicating its health benefits for adult patients. These benefits are partly attributed to changes, usually increased levels of the neuropeptide oxytocin. AIM: To investigate changes in oxytocin levels in hospitalized children meeting a certified Hospital Dog<sup>®</sup>.</p><p><strong>Method: </strong>Urine samples were collected between 25/02/2016 and 24/05/2017 from 35 hospitalized children (3-17 years) before and after each participant had a session with the Hospital Dog<sup>®</sup>. Oxytocin levels were analysed with an acetylcholinesterase (AChE) competitive enzyme-linked immunosorbent assay (ELISA). Creatinine levels were measured to determine the subject's fluid intake and then divided by the hormonal concentration (uOT pg/ml).</p><p><strong>Results: </strong>The mean level of uOT was 186.0 ± 236.7 (51.5-1349.5) pg/ml before and 137.3 ± 121.5 (30.7-591.3) pg/ml after the dog session (p = 0.010).</p><p><strong>Conclusion: </strong>Decreased levels of uOT were recorded during the study in which hospitalized children met a Hospital Dog<sup>®</sup>. The decreased OT levels are potentially the result of the intense activity the subject experienced with the dog during the interaction.</p>\",\"PeriodicalId\":9128,\"journal\":{\"name\":\"BMC Complementary Medicine and Therapies\",\"volume\":\"25 1\",\"pages\":\"327\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2025-09-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418696/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Complementary Medicine and Therapies\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12906-025-05076-6\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Complementary Medicine and Therapies","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12906-025-05076-6","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
Urinary oxytocin levels in children meeting a Hospital Dog®.
There has been growing interest in animal-assisted therapy (AAT) in recent decades due to increasing reports indicating its health benefits for adult patients. These benefits are partly attributed to changes, usually increased levels of the neuropeptide oxytocin. AIM: To investigate changes in oxytocin levels in hospitalized children meeting a certified Hospital Dog®.
Method: Urine samples were collected between 25/02/2016 and 24/05/2017 from 35 hospitalized children (3-17 years) before and after each participant had a session with the Hospital Dog®. Oxytocin levels were analysed with an acetylcholinesterase (AChE) competitive enzyme-linked immunosorbent assay (ELISA). Creatinine levels were measured to determine the subject's fluid intake and then divided by the hormonal concentration (uOT pg/ml).
Results: The mean level of uOT was 186.0 ± 236.7 (51.5-1349.5) pg/ml before and 137.3 ± 121.5 (30.7-591.3) pg/ml after the dog session (p = 0.010).
Conclusion: Decreased levels of uOT were recorded during the study in which hospitalized children met a Hospital Dog®. The decreased OT levels are potentially the result of the intense activity the subject experienced with the dog during the interaction.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
