近期性侵后PTSD和酒精滥用认知重构的随机对照试验：初步疗效和可行性

IF 4.5 2区心理学 Q1 PSYCHOLOGY, CLINICAL

Behaviour Research and Therapy Pub Date : 2025-08-28 DOI:10.1016/j.brat.2025.104847

Michele A. Bedard-Gilligan , Cynthia A. Stappenbeck , Heidi J. Ojalehto , Emily R. Dworkin , Jennifer M. Cadigan , Tracy Simpson , Debra L. Kaysen

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引用次数: 0

摘要

性侵犯是一个普遍存在的问题，尤其是对美国女大学生而言。尽管许多人会自然康复，但有相当一部分人会患上创伤后应激障碍（PTSD）或酒精滥用。急性干预可以预防慢性精神病理的发展。本研究测试了一种新开发的一疗程+四次辅导电话干预（BRITE）的疗效，该干预方法改编自认知处理疗法（CPT），是一种治疗慢性创伤后应激障碍的循证疗法。在性侵犯发生后的10周内，研究人员招募了18岁以上、有创伤后应激障碍和酒精滥用症状的女性，进行了一项比较BRITE和症状监测的随机对照试验。参与者（N = 57）为年轻人（M = 21.63岁），主要为白人（61.4%）。创伤后应激障碍和酒精使用在基线、每周5周和3个月的随访中由匿名评估者进行评估。与基线和3个月随访相比，BRITE组的受试者报告的PTSD症状（d = 2.69; 95% CI: 1.92, 3.45）明显少于症状监测组（d = 1.19; 95% CI: 0.59, 1.79）。对于酒精滥用，受试者报告从基线到3个月的BRITE随访(d = 0.63 （95% CI: 0.05, 1.20）和症状监测（d = 0.13; 95% CI: - 0.42, 0.69）中每天饮酒的饮酒量减少，尽管组间差异不显著。其他酒精使用结果也有类似的模式（即，严重的间歇性饮酒频率，酒精使用后果）。试点结果支持这种新开发的、简短的、可访问的认知方法，以促进弱势群体的急性康复。临床试验注册编号nct02808468。

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A pilot randomized controlled trial of cognitive restructuring for PTSD and alcohol misuse following recent sexual assault: Initial efficacy and feasibility

Sexual assault is a pervasive problem, particularly for US college women. Although many recover naturally, a significant minority develop posttraumatic stress disorder (PTSD) or alcohol misuse. Intervening acutely can prevent chronic psychopathology from developing. This study tested the efficacy of a newly developed one-session + four coaching call intervention (BRITE) adapted from Cognitive Processing Therapy (CPT), an evidence-based treatment for chronic PTSD. Individuals over 18, who identified as female, with symptoms of PTSD and alcohol misuse were recruited within 10 weeks of sexual assault for a RCT comparing BRITE to symptom monitoring. Participants (N = 57) were young (M = 21.63 years) and predominately White (61.4 %). PTSD and alcohol use were assessed at baseline, weekly for 5 weeks, and at 3-month follow-up by masked evaluators. Participants assigned to BRITE reported significantly less PTSD symptoms (d = 2.69; 95 % CI: 1.92, 3.45) than symptom monitoring (d = 1.19; 95 % CI: 0.59, 1.79), when comparing baseline vs. 3-month follow-up. For alcohol misuse, participants reported fewer drinks per drinking day from baseline to 3-month follow-up in BRITE (d = 0.63 (95 % CI: 0.05, 1.20) and symptom monitoring (d = 0.13; 95 % CI: −0.42, 0.69) although the group difference was not significant. There was a similar pattern for other alcohol use outcomes (i.e., heavy episodic drinking frequency, alcohol use consequences). Pilot findings support this newly developed, brief, and accessible cognitive approach for promoting acute recovery with a vulnerable population.

Clinical trials registration

NCT02808468.

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来源期刊

Behaviour Research and Therapy PSYCHOLOGY, CLINICAL-

CiteScore

7.50

自引率

7.30%

发文量

148

期刊介绍： The major focus of Behaviour Research and Therapy is an experimental psychopathology approach to understanding emotional and behavioral disorders and their prevention and treatment, using cognitive, behavioral, and psychophysiological (including neural) methods and models. This includes laboratory-based experimental studies with healthy, at risk and subclinical individuals that inform clinical application as well as studies with clinically severe samples. The following types of submissions are encouraged: theoretical reviews of mechanisms that contribute to psychopathology and that offer new treatment targets; tests of novel, mechanistically focused psychological interventions, especially ones that include theory-driven or experimentally-derived predictors, moderators and mediators; and innovations in dissemination and implementation of evidence-based practices into clinical practice in psychology and associated fields, especially those that target underlying mechanisms or focus on novel approaches to treatment delivery. In addition to traditional psychological disorders, the scope of the journal includes behavioural medicine (e.g., chronic pain). The journal will not consider manuscripts dealing primarily with measurement, psychometric analyses, and personality assessment.