自体口腔黏膜上皮移植治疗双侧角膜缘干细胞缺乏症。

Q3 Medicine

Vestnik oftalmologii Pub Date : 2025-01-01 DOI:10.17116/oftalma202514104196

R S Isabekov, B E Malyugin, A M Gelyastanov, M Yu Gerasimov

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引用次数: 0

摘要

本文综述了俄罗斯和国际上关于治疗双侧角膜缘干细胞缺乏症（LSCD）的文献，重点介绍了简单口腔黏膜上皮移植（SOMET）作为修复眼表的手术方法。当代文献报道了64例SOMET用于治疗双侧LSCD：化学烧伤35例，热烧伤16例，Stevens-Johnson综合征7例，角膜炎1例，瘢痕性类天疱疮1例，皮样病变1例，药物性LSCD（丝裂霉素C） 1例等。值得注意的是，所有移植均获得了完整的上皮化，其中3例随后进行了穿透性角膜移植术，并获得了良好的功能和解剖结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Autologous oral mucosal epithelial transplantation in the treatment of bilateral limbal stem cell deficiency].

This review analyzes Russian and international literature on the treatment of bilateral limbal stem cell deficiency (LSCD), focusing on the use of Simple Oral Mucosal Epithelial Transplantation (SOMET) as a surgical method for restoring the ocular surface. Contemporary sources report 64 cases of SOMET used in the treatment of bilateral LSCD: 35 cases of chemical burns, 16 of thermal burns, 7 cases of Stevens-Johnson syndrome, 1 keratitis, 1 cicatricial pemphigoid, 1 dermoid, 1 case of drug-induced LSCD (mitomycin C), etc. Notably, all transplantations resulted in complete epithelialization, and in 3 cases, penetrating keratoplasty was subsequently performed with favorable functional and anatomical outcomes.

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来源期刊

Vestnik oftalmologii Medicine-Ophthalmology

CiteScore

0.80

自引率

0.00%

发文量

129

期刊介绍： The journal publishes materials on the diagnosis and treatment of eye diseases, hygiene of vision, prevention of ophthalmic affections, history of Russian ophthalmology, organization of ophthalmological aid to the population, as well as the problems of special equipment. Original scientific articles and surveys on urgent problems of theory and practice of Russian and foreign ophthalmology are published. The journal contains book reviews on ophthalmology, information on the activities of ophthalmologists" scientific societies, chronicle of congresses and conferences.The journal is intended for ophthalmologists and scientific workers dealing with clinical problems of diseases of the eye and physiology of vision.