肉桂致接触性口炎74例回顾性分析并文献复习。

IF 2.9 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Oral diseases Pub Date : 2025-09-07 DOI:10.1111/odi.70081
Eleni-Marina Kalogirou, Aikaterini Aktypi-Bampouranou, Marianna Vasilaki, Konstantina Chatzidimitriou, Konstantinos I Tosios
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引用次数: 0

摘要

目的:肉桂诱导的接触性口炎(CCS)是一种与含肉桂产物(ccp)相关的超敏反应。我们对74例咀嚼口香糖或糖果引起的CCS进行了回顾性研究,并复习了文献。材料和方法:这是一项对2010-2025年间诊断的CCS病例的回顾性研究,其特征是病变与食用含肉桂的口香糖或糖果的时间相关;停用CCPs后病变的消退情况;只要这些ccp不重复使用,就不会复发。文献回顾了类似的CCS病例,记录了相关的病史和至少一个临床/组织病理图像。结果:74例患者被诊断为CCS,主要累及颊黏膜(67/74)和/或侧舌(50/74)。7例患者出现白色地衣样或斑块型病变,26例患者出现红斑/糜烂/溃疡性病变,41例患者出现白红色合并病变。在所有病例中,停用ccp可在一周内完全解决问题。文献综述得出了40例与口香糖、糖果或薄荷糖有关的CCS病例。结论:在咬合平面出现红斑和/或白色病变应引起对CCS的怀疑,可根据患者的病史和临床表现进行诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cinnamon-Induced Contact Stomatitis: A Retrospective Study of 74 Cases and Literature Review.

Objective: Cinnamon-induced contact stomatitis (CCS) is a hypersensitivity reaction associated with cinnamon-containing products (CCPs). We performed a retrospective study of 74 cases of CCS induced by chewing gums or candies and reviewed the literature.

Materials and methods: This is a retrospective study of CCS cases, diagnosed during 2010-2025, characterised by temporal association of lesions with the consumption of cinnamon-containing chewing gums or candies; lesion's resolution after discontinuation of those CCPs; and absence of recurrence as long as those CCPs were not re-used. The literature was reviewed for similar CCS cases, documented by relevant history and at least one clinical/histopathological image.

Results: Seventy-four patients were diagnosed with CCS that mainly involved the buccal mucosa (67/74) and/or lateral tongue (50/74). White lichenoid or plaque-type lesions were observed in seven patients, erythematous/erosive/ulcerative lesions in 26 patients, and combined whitish-red lesions in 41 patients. Discontinuation of CCPs resulted in complete resolution within a week in all cases. The literature review yielded 40 well-documented cases of CCS related to chewing gums, candies, or mints.

Conclusion: The presence of erythematous and/or white lesions at the occlusal plane should raise suspicion of CCS that can be diagnosed based on the patient's history and clinical presentation.

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来源期刊
Oral diseases
Oral diseases 医学-牙科与口腔外科
CiteScore
7.60
自引率
5.30%
发文量
325
审稿时长
4-8 weeks
期刊介绍: Oral Diseases is a multidisciplinary and international journal with a focus on head and neck disorders, edited by leaders in the field, Professor Giovanni Lodi (Editor-in-Chief, Milan, Italy), Professor Stefano Petti (Deputy Editor, Rome, Italy) and Associate Professor Gulshan Sunavala-Dossabhoy (Deputy Editor, Shreveport, LA, USA). The journal is pre-eminent in oral medicine. Oral Diseases specifically strives to link often-isolated areas of dentistry and medicine through broad-based scholarship that includes well-designed and controlled clinical research, analytical epidemiology, and the translation of basic science in pre-clinical studies. The journal typically publishes articles relevant to many related medical specialties including especially dermatology, gastroenterology, hematology, immunology, infectious diseases, neuropsychiatry, oncology and otolaryngology. The essential requirement is that all submitted research is hypothesis-driven, with significant positive and negative results both welcomed. Equal publication emphasis is placed on etiology, pathogenesis, diagnosis, prevention and treatment.
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