Gayathri Loganathan, Pirangi Srikanth, Khaja Moinuddin Shaik and Sukhendu Nandi
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Carbon quantum dot-based fluorometric detection of nitrosamine impurities in active pharmaceutical ingredients
Nitrosamines are genotoxic, mutagenic impurities and are widely encountered in the global landscape of the pharmaceutical industry. There is a need for rapid detection of nitrosamines in a pharmaceutical product. Here, we report the synthesis of carbon quantum dots (CQDs) using a readily available carbon precursor. These CQDs showed attractive fluorescence properties and were employed to fabricate a portable device for the fluorometric detection of nitrosamine impurities in a drug matrix.
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