使用特低黏度的经静脉栓塞治疗脑动静脉畸形:初步经验和技术见解。

IF 2.1 4区 医学 Q3 Medicine
Juan Carlos Llibre-Guerra, Miguel Castaño Blázquez, Leopoldo Guimaraens, José Manuel Pumar, Pascal J Mosimann, Alberto Gil-García
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引用次数: 0

摘要

背景与目的本研究介绍了我们在经静脉治疗脑动静脉畸形(bAVMs)中使用ihtotura的初步经验,ihtotura是一种具有超低粘度变异的新型无黏附液体栓塞剂。我们评估了该剂的性能,并将其与目前可用的其他超低粘度选择的优势进行了比较。材料与方法采用经静脉逆行高压锅技术(TVRPCT)治疗5例(女3例,男2例,平均年龄33岁,年龄范围20 ~ 55岁)脑脊髓炎破裂患者。3例患者对较大的bavm进行了分期栓塞,最后一次使用TVRPCT,而2例较小的bavm患者在一次治疗中。结果100%的患者完全闭塞。每次经静脉使用ihttotura的平均体积为7.9 mL(范围2-14 mL)±4.8。ihtObtura 15和ihtObtura 12联合应用3例,ihtObtura 15单独应用2例。在6个月和24个月的随访中维持完全血管造影闭塞。3例患者的临床结果改善,2例保持不变(mRS = 0)。结论特低黏度TVRPCT与其他特低黏度非黏性液体栓塞剂一样安全有效。经静脉途径ihtotura的渗透、扩散和分布最佳,未见血管破裂或外渗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transvenous curative embolization of brain arteriovenous malformations using extra-low viscosity ihtObtura versions: Initial experience and technical insights.

Background and purposeThis study presents our initial experience using ihtObtura, a novel nonadhesive liquid embolic agent with extra-low viscosity variants, in transvenous curative embolization of brain arteriovenous malformations (bAVMs). We assess the agent's performance and compare its advantages with other extra-low viscosity options currently available.Materials and methodsFive patients (three females, two males; mean age, 33 years; range, 20-55 years) with ruptured bAVMs were treated using the transvenous retrograde pressure cooker technique (TVRPCT). Three patients underwent staged embolization for large bAVMs, with the final session performed using TVRPCT, while two patients with smaller bAVMs were treated in a single session.ResultsComplete obliteration was achieved in 100% of patients. The mean volume of ihtObtura used per transvenous session was 7.9 mL (range, 2-14 mL) ± 4.8. A combination of ihtObtura 15 and ihtObtura 12 was used in three cases, while ihtObtura 15 alone was used in two cases. Complete angiographic occlusion was sustained at six and 24 months follow-up. Clinical outcomes improved in three patients and remained unchanged in two (mRS = 0).ConclusionsThe TVRPCT with extra-low viscosity ihtObtura appears to be as safe and effective as other extra-low viscosity nonadhesive liquid embolic agents for curative treatment of bAVMs. The penetration, diffusion, and distribution of ihtObtura through the transvenous route were optimal, with no observed vascular rupture or extravasation.

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来源期刊
CiteScore
2.80
自引率
11.80%
发文量
192
审稿时长
6-12 weeks
期刊介绍: Interventional Neuroradiology (INR) is a peer-reviewed clinical practice journal documenting the current state of interventional neuroradiology worldwide. INR publishes original clinical observations, descriptions of new techniques or procedures, case reports, and articles on the ethical and social aspects of related health care. Original research published in INR is related to the practice of interventional neuroradiology...
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