艰难梭菌感染的诊断方法。

IF 4.1 3区医学 Q1 IMMUNOLOGY

Infectious disease clinics of North America Pub Date : 2025-09-06 DOI:10.1016/j.idc.2025.07.014

Parul Berry, Sahil Khanna

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引用次数: 0

摘要

本文提供了临床重点概述艰难梭菌感染（CDI）的诊断，强调需要检测只有症状的患者，并区分真正的感染和定植。它回顾了多步骤诊断算法配对谷氨酸脱氢酶（GDH）检测或核酸扩增试验（NAAT）与毒素分析，以提高准确性。本文讨论了仅pcr方法的局限性，并着重强调了临床相关性。基于指南的建议贯穿始终，为临床医生在住院和门诊环境中管理CDI提供循证指导。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Diagnostic Approaches for Clostridioides difficile Infection.

This article offers a clinically focused overview of Clostridioides difficile infection (CDI) diagnosis, emphasizing the need to test only symptomatic patients and to distinguish true infection from colonization. It reviews multistep diagnostic algorithms that pair glutamate dehydrogenase (GDH) testing or nucleic acid amplification tests (NAAT) with toxin assays to improve accuracy. The limitations of PCR-only approaches are discussed, with a strong emphasis on clinical correlation. Guideline-based recommendations are integrated throughout, providing evidence-based direction for clinicians managing CDI in both inpatient and outpatient settings.

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来源期刊

Infectious disease clinics of North America 医学-传染病学

CiteScore

8.30

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Infectious Disease Clinics of North America updates you on the latest trends in the clinical diagnosis and management of patients with infectious diseases, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Each issue focuses on a single topic in infectious disease, including clinical microbiology, compromised host infections, gastrointestinal infections, global health, hepatitis, HIV/AIDS, hospital-acquired infections, travel medicine, infection control, bacterial infections, sexually transmitted diseases, urinary tract infections, and viral infections.