2024年8月至11月瑞典与苜蓿芽有关的36型鼠伤寒沙门氏菌多聚集性暴发。

IF 2.2 4区 医学 Q3 INFECTIOUS DISEASES
Kate Lillepold, Nadja Karamehmedovic, Ioana Bujila, Anna Ohlson, Joanna Nederby Öhd, Ingela Hall, Gunilla Ockborn, Mats Lindblad, Ilias Galanis, Moa Rehn, Rikard Dryselius
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引用次数: 0

摘要

鼠伤寒沙门氏菌序列型(ST) 36在瑞典是一种罕见的序列型。2024年8 - 11月,全国共报告鼠伤寒沙门菌ST36病例100例。0-10岁(17%)和41-50岁(20%)的病例比例最高,其中女性占总病例的65%。鼠伤寒沙门氏菌ST36分离株的微生物学分析鉴定出9个聚类和5个单独的菌株,它们在53个单核苷酸多态性中聚类。一项匹配的病例对照研究发现,病例与食用苜蓿芽有关(校正优势比= 8.94,95% CI: 2.96-27.1)。追溯调查发现,瑞典两家苜蓿芽生产商使用的种子可能是此次疫情的源头,尽管对生产商生产的苜蓿芽进行的微生物分析未发现沙门氏菌。然而,持续的国际调查进一步表明来自同一来源的种子,支持苜蓿种子是瑞典疫情的最终来源。我们的调查和结果表明,苜蓿芽可能含有沙门氏菌,从而对消费者构成健康风险。我们强调苜蓿种子和豆芽的初级生产者需要识别和防止可能的污染点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multi-cluster outbreak of Salmonella Typhimurium sequence type 36 linked to alfalfa sprouts, Sweden, August-November 2024.

Salmonella Typhimurium sequence type (ST) 36 is a rare sequence type in Sweden. During August-November 2024, 100 cases of Salmonella Typhimurium ST36 were reported nationwide. The highest proportions of cases were observed among individuals aged 0-10 years (17%) and 41-50 years (20%), with females representing 65% of the total cases. Microbiological analysis of the S. Typhimurium ST36 isolates identified nine clusters and five individual strains clustering within 53 single-nucleotide polymorphisms. A matched case-control study found cases to be associated with the consumption of alfalfa sprouts (adjusted odds ratio = 8.94, 95% CI: 2.96-27.1). Trace-back investigation identified seeds used by two alfalfa sprout producers in Sweden as the likely source of the outbreak, although microbiological analysis of sprouted alfalfa seeds from the producers did not detect Salmonella. However, continued international investigations further implicated seeds sourced from the same origin, supporting that alfalfa seeds were the ultimate source of the Swedish outbreak. Our investigation and findings indicate that alfalfa sprouts may contain Salmonella and thus pose a health risk to consumers. We emphasize the need for primary producers of alfalfa seeds and sprouts to identify and prevent possible contamination points.

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来源期刊
Epidemiology and Infection
Epidemiology and Infection 医学-传染病学
CiteScore
4.10
自引率
2.40%
发文量
366
审稿时长
3-6 weeks
期刊介绍: Epidemiology & Infection publishes original reports and reviews on all aspects of infection in humans and animals. Particular emphasis is given to the epidemiology, prevention and control of infectious diseases. The scope covers the zoonoses, outbreaks, food hygiene, vaccine studies, statistics and the clinical, social and public-health aspects of infectious disease, as well as some tropical infections. It has become the key international periodical in which to find the latest reports on recently discovered infections and new technology. For those concerned with policy and planning for the control of infections, the papers on mathematical modelling of epidemics caused by historical, current and emergent infections are of particular value.
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