{"title":"益生菌对两种不同海拔地区饲养肉鸡粪便微生物群的影响","authors":"Swati, Mayarngam Khansu, Deachan Chuskit, Ashish Kumar Srivastava, Jasdeep Singh, Om Prakash Chaurasia, Lilly Ganju","doi":"10.1007/s13205-025-04446-8","DOIUrl":null,"url":null,"abstract":"<p><p>Poultry farming in high altitude like Leh-Ladakh, India is a challenge due to hypobaric-hypoxia environment and probiotic may support gut health, feed efficiency, production and adaptation in chicken. Therefore, the present study was performed to elucidate the role of probiotic on broiler chicken gut microflora from two different high altitude locations; Leh and Chang La. No change was found on the growth of the broiler with probiotic intervention. The fecal microbiota study revealed that the microbial abundance was higher in Chang La samples as compared to Leh samples. At taxonomic level, Chang La samples were dominated by <i>Firmicutes, Proteobacteria, Bacteroides, Actinobacteria</i> phylum whereas in Leh samples, <i>Elusimicrobia</i> was dominant followed by <i>Nitrospirae</i>. Probiotic treatment had minimal effect on chicken gut microflora at the genus and species level. The probiotic effect on gut microflora of Leh broilers was more diverse as compared to the control group. Contrary, to the Chang La group, the probiotic effect had less diverse microbial population as compared to the control group; maintaining the gut microbiome homeostasis of broiler chicken in such extreme high altitude. The microbial functional annotation revealed differences majorly in pathways related to maintenance of cellular energy homeostasis, glycan and carbohydrate metabolisms, regulatory systems, signaling pathways, environmental processing and cell-cell signaling. The findings of the study are an indicative of diversified gut microflora of broiler chicken from two distinct high altitude locations. The study can further be useful to explore the role of different probiotic strains, their doses or delivery methods for the adaptation of these birds at such extreme environments.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s13205-025-04446-8.</p>","PeriodicalId":7067,"journal":{"name":"3 Biotech","volume":"15 10","pages":"328"},"PeriodicalIF":2.9000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408439/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effect of probiotic on fecal microbiome of broiler chicken reared at two different high altitude locations.\",\"authors\":\"Swati, Mayarngam Khansu, Deachan Chuskit, Ashish Kumar Srivastava, Jasdeep Singh, Om Prakash Chaurasia, Lilly Ganju\",\"doi\":\"10.1007/s13205-025-04446-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Poultry farming in high altitude like Leh-Ladakh, India is a challenge due to hypobaric-hypoxia environment and probiotic may support gut health, feed efficiency, production and adaptation in chicken. Therefore, the present study was performed to elucidate the role of probiotic on broiler chicken gut microflora from two different high altitude locations; Leh and Chang La. No change was found on the growth of the broiler with probiotic intervention. The fecal microbiota study revealed that the microbial abundance was higher in Chang La samples as compared to Leh samples. At taxonomic level, Chang La samples were dominated by <i>Firmicutes, Proteobacteria, Bacteroides, Actinobacteria</i> phylum whereas in Leh samples, <i>Elusimicrobia</i> was dominant followed by <i>Nitrospirae</i>. Probiotic treatment had minimal effect on chicken gut microflora at the genus and species level. The probiotic effect on gut microflora of Leh broilers was more diverse as compared to the control group. Contrary, to the Chang La group, the probiotic effect had less diverse microbial population as compared to the control group; maintaining the gut microbiome homeostasis of broiler chicken in such extreme high altitude. The microbial functional annotation revealed differences majorly in pathways related to maintenance of cellular energy homeostasis, glycan and carbohydrate metabolisms, regulatory systems, signaling pathways, environmental processing and cell-cell signaling. The findings of the study are an indicative of diversified gut microflora of broiler chicken from two distinct high altitude locations. The study can further be useful to explore the role of different probiotic strains, their doses or delivery methods for the adaptation of these birds at such extreme environments.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s13205-025-04446-8.</p>\",\"PeriodicalId\":7067,\"journal\":{\"name\":\"3 Biotech\",\"volume\":\"15 10\",\"pages\":\"328\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408439/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"3 Biotech\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1007/s13205-025-04446-8\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/9/3 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"3 Biotech","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s13205-025-04446-8","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/3 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
Effect of probiotic on fecal microbiome of broiler chicken reared at two different high altitude locations.
Poultry farming in high altitude like Leh-Ladakh, India is a challenge due to hypobaric-hypoxia environment and probiotic may support gut health, feed efficiency, production and adaptation in chicken. Therefore, the present study was performed to elucidate the role of probiotic on broiler chicken gut microflora from two different high altitude locations; Leh and Chang La. No change was found on the growth of the broiler with probiotic intervention. The fecal microbiota study revealed that the microbial abundance was higher in Chang La samples as compared to Leh samples. At taxonomic level, Chang La samples were dominated by Firmicutes, Proteobacteria, Bacteroides, Actinobacteria phylum whereas in Leh samples, Elusimicrobia was dominant followed by Nitrospirae. Probiotic treatment had minimal effect on chicken gut microflora at the genus and species level. The probiotic effect on gut microflora of Leh broilers was more diverse as compared to the control group. Contrary, to the Chang La group, the probiotic effect had less diverse microbial population as compared to the control group; maintaining the gut microbiome homeostasis of broiler chicken in such extreme high altitude. The microbial functional annotation revealed differences majorly in pathways related to maintenance of cellular energy homeostasis, glycan and carbohydrate metabolisms, regulatory systems, signaling pathways, environmental processing and cell-cell signaling. The findings of the study are an indicative of diversified gut microflora of broiler chicken from two distinct high altitude locations. The study can further be useful to explore the role of different probiotic strains, their doses or delivery methods for the adaptation of these birds at such extreme environments.
Supplementary information: The online version contains supplementary material available at 10.1007/s13205-025-04446-8.
3 BiotechAgricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)
CiteScore
6.00
自引率
0.00%
发文量
314
期刊介绍:
3 Biotech publishes the results of the latest research related to the study and application of biotechnology to:
- Medicine and Biomedical Sciences
- Agriculture
- The Environment
The focus on these three technology sectors recognizes that complete Biotechnology applications often require a combination of techniques. 3 Biotech not only presents the latest developments in biotechnology but also addresses the problems and benefits of integrating a variety of techniques for a particular application. 3 Biotech will appeal to scientists and engineers in both academia and industry focused on the safe and efficient application of Biotechnology to Medicine, Agriculture and the Environment.