Subhasis Chattopadhyay, Robin Durník, Dr. Anniina Kiesilä, Dr. Elina Kalenius, Dr. Juha M. Linnanto, Assoc.Prof. Pavel Babica, Dr. Jan Kuta, Prof.Dr. Radek Marek, Dr. Ondřej Jurček
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Inside Back Cover: Flexibility-Aided Orientational Self-Sorting and Transformations of Bioactive Homochiral Cuboctahedron Pd12L16 (Angew. Chem. 37/2025)
With great respect for bears, which, in the past, were used to harvest their bile containing ursodeoxycholic acid – a key building block in this study – we developed a flexible and unsymmetric coordination ligand L. L reacts with salts of shiny palladium forming helical Pd6L8 and Pd12L16 cages via flexibility-aided orientational self-sorting. The cages undergo structural transformations induced by changing reaction conditions and exhibit toxicity in vitro using spheroids of hepatic cells HepG2. Details of the study are reported by Ondřej Jurček et al. in their Research Article (e202513902).
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