光学相干断层成像血管造影中的腔体高反射率内容和间隔运动伪影。

IF 2.6 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-09-04 DOI:10.1016/j.pdpdt.2025.105211

Shaochi Zhang , Yunkao Zeng , Feng Wen , Xiongze Zhang

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引用次数: 0

摘要

目的：探讨在多处眼底异常的面部光学相干断层血管造影（OCTA）中出现的腔内高反射物和间隔运动伪影（CHASMA）的特征。方法：这是一项横断面观察性研究。受试者的血管外OCTA信号来自腔的高反射性内容物和/或间隔。评估正面OCTA图像和相应的截面光学相干断层扫描（OCT）图像的特征。根据解剖位置对CHASMA进行分类。结果：对25例受试者25只眼的图像进行分析。在玻璃体腔、视网膜内囊肿、视网膜下间隙和色素上皮脱离（PED）腔内的颗粒中发现CHASMA。所有OCTA图像中的CHASMA区域均与相应结构oct上的高反射腔物和/或腔间间隔相关。根据解剖位置，CHASMA分为玻璃体、视网膜内、视网膜下和PED-CHASMA。玻璃体出血、玻璃体漂浮物继发玻璃体混浊14眼，归类为玻璃体裂口。6眼出现囊样黄斑水肿，1眼出现亚内限制膜出血。2眼视网膜下出血或细菌脱离为视网膜下CHASMA， 2眼出血性PED为PED CHASMA。结论：不同眼底水平的空腔可能允许内容物和腔间隔的宏观运动，产生不同的运动伪影。这些运动伪影被称为CHASMA，在解释正面OCTA图像时应注意。

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Cavity hyperreflective-content and septum's motion artifact in optical coherence tomography angiography

Purpose

To characterize the cavity hyperreflective-content and septum's motion artifact (CHASMA) in en face optical coherence tomography angiography (OCTA) across multiple ocular fundus abnormalities.

Methods

This was a cross-sectional, observational study. Subjects with extravascular OCTA signals arising from the cavity’s hyperreflective-content and/or septum were enrolled. Characteristics of en face OCTA images and corresponding cross-sectional optical coherence tomography (OCT) images were evaluated. CHASMA was classified according to anatomic location.

Results

The images of 25 eyes from 25 subjects were analyzed. CHASMA was identified in particles within the vitreous cavity, intraretinal cyst, subretinal space and the pigment epithelial detachment (PED) cavities. The regions of CHASMA in all included OCTA images were associated with hyperreflective cavity content and/or intercavity septa on the corresponding structural OCT. CHASMA was classified as vitreous, intraretinal, subretinal and PED-CHASMA according to the anatomic locations. Fourteen eyes with vitreous opacities secondary to vitreous hemorrhage, vitreous floater were classified as vitreous CHASMA. Six eyes with cystoid macular edema and 1eye with sub‐internal limiting membrane hemorrhage were classified as intraretinal CHASMA. Two eyes with subretinal hemorrhage or bacillary detachment were classify as subretinal CHASMA and 2 eyes with hemorrhagic PED were classified as PED CHASMA.

Conclusions

The cavities at different fundus levels may allow for macroscopic motion of the contents and intercavity septa, producing various motion artifacts. These motion artifacts are termed CHASMA and cautions should be taken when interpreting en face OCTA images.

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.