{"title":"人体测量参数与儿童和青少年近视的关系：系统回顾和荟萃分析。","authors":"Zhong Guan, Yuzhu Luo, Heting Liu, Shuman Tao","doi":"10.1038/s41366-025-01900-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To systematically evaluate the association between anthropometric parameter and myopia in children and adolescents.</p><p><strong>Methods: </strong>PubMed, Web of Science, EBSCO, Embase, CNKI, CBM, WanFang Data, and VIP databases were searched from inception to June, 2025. We collected cross-sectional studies on the association between anthropometric parameter and myopia in children and adolescents aged 0-25 years, including body mass index (BMI) and weight-adjusted waist index (WWI). After independently screening the literature, extracting the data and evaluating the risk of bias in the included studies by 2 researchers, meta-analysis was performed using Stata 18.0 software.</p><p><strong>Results: </strong>A total of 18 cross-sectional studies were included, from which 1,505,099 participants were analyzed. Meta-analysis results suggested a positive relationship between anthropometric parameters and myopia. The pooled OR for overweight was 1.27 (95%CI: 1.08 ~ 1.51; I<sup>2</sup> = 81.6%; P < 0.001). After excluding outliers, the pooled OR for overweight was 1.14 (95% CI: 1.13 ~ 1.15; I<sup>2</sup> = 0.0%; P = 0.444). The pooled OR for obesity was 1.25 (95%CI: 1.12 ~ 1.39; I<sup>2</sup> = 88.3%; P < 0.001). The results demonstrated inconsistency when subgroup analyses were performed based on age, geographic regions, visual acuity measurement methods, sample characteristics, whether covariates were adjusted in the original data, and whether one of 3 main confounders (parental myopia, outdoor time, or near work) was controlled. Results of meta-regression analysis showed that the publication year was not a source of heterogeneity across overweight, obesity and BMI/WWI groups. Subgroup evaluation revealed that a pooled value was 1.08 (95%CI: 1.00 ~ 1.18; I<sup>2</sup> = 88.9%; P < 0.001) for BMI in BMI/WWI group. The results of Egger's test also suggested that there was no significant publication bias in overweight, obesity, and BMI/WWI groups, respectively.</p><p><strong>Conclusions: </strong>Our findings support that anthropometric parameter was significantly associated with myopia in children and adolescents. However, given the limitations of the included cross-sectional studies, prospective studies are warranted to further investigate this issue.</p>","PeriodicalId":14183,"journal":{"name":"International Journal of Obesity","volume":" ","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association of anthropometric parameter with myopia in children and adolescents: A systematic review and meta-analysis.\",\"authors\":\"Zhong Guan, Yuzhu Luo, Heting Liu, Shuman Tao\",\"doi\":\"10.1038/s41366-025-01900-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To systematically evaluate the association between anthropometric parameter and myopia in children and adolescents.</p><p><strong>Methods: </strong>PubMed, Web of Science, EBSCO, Embase, CNKI, CBM, WanFang Data, and VIP databases were searched from inception to June, 2025. We collected cross-sectional studies on the association between anthropometric parameter and myopia in children and adolescents aged 0-25 years, including body mass index (BMI) and weight-adjusted waist index (WWI). After independently screening the literature, extracting the data and evaluating the risk of bias in the included studies by 2 researchers, meta-analysis was performed using Stata 18.0 software.</p><p><strong>Results: </strong>A total of 18 cross-sectional studies were included, from which 1,505,099 participants were analyzed. Meta-analysis results suggested a positive relationship between anthropometric parameters and myopia. The pooled OR for overweight was 1.27 (95%CI: 1.08 ~ 1.51; I<sup>2</sup> = 81.6%; P < 0.001). After excluding outliers, the pooled OR for overweight was 1.14 (95% CI: 1.13 ~ 1.15; I<sup>2</sup> = 0.0%; P = 0.444). The pooled OR for obesity was 1.25 (95%CI: 1.12 ~ 1.39; I<sup>2</sup> = 88.3%; P < 0.001). The results demonstrated inconsistency when subgroup analyses were performed based on age, geographic regions, visual acuity measurement methods, sample characteristics, whether covariates were adjusted in the original data, and whether one of 3 main confounders (parental myopia, outdoor time, or near work) was controlled. Results of meta-regression analysis showed that the publication year was not a source of heterogeneity across overweight, obesity and BMI/WWI groups. Subgroup evaluation revealed that a pooled value was 1.08 (95%CI: 1.00 ~ 1.18; I<sup>2</sup> = 88.9%; P < 0.001) for BMI in BMI/WWI group. The results of Egger's test also suggested that there was no significant publication bias in overweight, obesity, and BMI/WWI groups, respectively.</p><p><strong>Conclusions: </strong>Our findings support that anthropometric parameter was significantly associated with myopia in children and adolescents. However, given the limitations of the included cross-sectional studies, prospective studies are warranted to further investigate this issue.</p>\",\"PeriodicalId\":14183,\"journal\":{\"name\":\"International Journal of Obesity\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2025-09-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Obesity\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41366-025-01900-8\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Obesity","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41366-025-01900-8","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
摘要
目的：系统评价儿童青少年人体测量参数与近视的关系。方法：检索自建库至2025年6月的PubMed、Web of Science、EBSCO、Embase、CNKI、CBM、万方数据、VIP等数据库。我们收集了0-25岁儿童和青少年的人体测量参数与近视关系的横断面研究，包括体重指数（BMI）和体重调整腰围指数（WWI）。2位研究者独立筛选文献、提取资料并评估纳入研究的偏倚风险后，使用Stata 18.0软件进行meta分析。结果：共纳入18项横断面研究，分析了1,505,099名参与者。meta分析结果显示，人体测量参数与近视呈正相关。池或超重为1.27 (95% ci: 1.08 ~ 1.51; I2 = 81.6%; P 2 = 0.0%; P = 0.444)。肥胖的合并OR为1.25 （95%CI: 1.12 ~ 1.39; I2 = 88.3%; P 2 = 88.9%； P）结论：我们的研究结果支持人体测量参数与儿童和青少年近视的显著相关。然而，考虑到所纳入的横断面研究的局限性，前瞻性研究有必要进一步研究这一问题。
Association of anthropometric parameter with myopia in children and adolescents: A systematic review and meta-analysis.
Objective: To systematically evaluate the association between anthropometric parameter and myopia in children and adolescents.
Methods: PubMed, Web of Science, EBSCO, Embase, CNKI, CBM, WanFang Data, and VIP databases were searched from inception to June, 2025. We collected cross-sectional studies on the association between anthropometric parameter and myopia in children and adolescents aged 0-25 years, including body mass index (BMI) and weight-adjusted waist index (WWI). After independently screening the literature, extracting the data and evaluating the risk of bias in the included studies by 2 researchers, meta-analysis was performed using Stata 18.0 software.
Results: A total of 18 cross-sectional studies were included, from which 1,505,099 participants were analyzed. Meta-analysis results suggested a positive relationship between anthropometric parameters and myopia. The pooled OR for overweight was 1.27 (95%CI: 1.08 ~ 1.51; I2 = 81.6%; P < 0.001). After excluding outliers, the pooled OR for overweight was 1.14 (95% CI: 1.13 ~ 1.15; I2 = 0.0%; P = 0.444). The pooled OR for obesity was 1.25 (95%CI: 1.12 ~ 1.39; I2 = 88.3%; P < 0.001). The results demonstrated inconsistency when subgroup analyses were performed based on age, geographic regions, visual acuity measurement methods, sample characteristics, whether covariates were adjusted in the original data, and whether one of 3 main confounders (parental myopia, outdoor time, or near work) was controlled. Results of meta-regression analysis showed that the publication year was not a source of heterogeneity across overweight, obesity and BMI/WWI groups. Subgroup evaluation revealed that a pooled value was 1.08 (95%CI: 1.00 ~ 1.18; I2 = 88.9%; P < 0.001) for BMI in BMI/WWI group. The results of Egger's test also suggested that there was no significant publication bias in overweight, obesity, and BMI/WWI groups, respectively.
Conclusions: Our findings support that anthropometric parameter was significantly associated with myopia in children and adolescents. However, given the limitations of the included cross-sectional studies, prospective studies are warranted to further investigate this issue.
期刊介绍：
The International Journal of Obesity is a multi-disciplinary forum for research describing basic, clinical and applied studies in biochemistry, physiology, genetics and nutrition, molecular, metabolic, psychological and epidemiological aspects of obesity and related disorders.
We publish a range of content types including original research articles, technical reports, reviews, correspondence and brief communications that elaborate on significant advances in the field and cover topical issues.
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