Philipp Mench, T Koppius, J Ewen, W Rippe, J O Radecke, B Tari, M Heath, S Borgwardt, B Wilms, A Sprenger, R Lencer
{"title":"精神分裂症谱系障碍的认知控制与长期运动活动有关,而不是单次运动。","authors":"Philipp Mench, T Koppius, J Ewen, W Rippe, J O Radecke, B Tari, M Heath, S Borgwardt, B Wilms, A Sprenger, R Lencer","doi":"10.1007/s00406-025-02101-0","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Patients with schizophrenia spectrum disorder (SSD) suffer from impaired cognitive functions. Previous studies in healthy individuals have shown that a single bout of physical exercise benefits cognitive functions. Such enhancements in cognitive function would be highly beneficial, particularly for patients with SSD, as cognitive abilities play a vital role in both mental and physical health.</p><p><strong>Methods: </strong>We examined the impact of a single bout of aerobic exercise on cognitive function in 25 patients with SSD and 24 healthy controls. Participants performed a single bout of aerobic exercise adjusted to their individual fitness level. Cognitive function was examined pre- and postexercise via oculomotor tasks consisting of saccadic (i.e., pro- and antisaccades) and smooth pursuit eye movements (SPEM). Furthermore, long-term physical fitness and movement activity were assessed through an anaerobic threshold testing and self-reports of physical activity.</p><p><strong>Results: </strong>As expected, SSD-patients showed higher antisaccade error rates and were impaired in both SPEM initiation and maintenance with higher disorganization levels being related to lower SPEM performance. Neither the patient nor control group benefited from a single bout of exercise in terms of improved saccade or SPEM performance. However, higher fitness levels and more extensive long-term movement activity were associated with lower antisaccade error rates in patients.</p><p><strong>Conclusion: </strong>These findings do not demonstrate a single bout postexercise benefit in cognition; however, results indicate an association between greater cognitive control and long-term movement activity and thus underscore the importance of conducting further investigations into long-term exercise interventions as a complementary therapeutic approach.</p>","PeriodicalId":11822,"journal":{"name":"European Archives of Psychiatry and Clinical Neuroscience","volume":" ","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cognitive control in schizophrenia spectrum disorders is associated with long-term movement activity rather than single-bout exercise.\",\"authors\":\"Philipp Mench, T Koppius, J Ewen, W Rippe, J O Radecke, B Tari, M Heath, S Borgwardt, B Wilms, A Sprenger, R Lencer\",\"doi\":\"10.1007/s00406-025-02101-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Patients with schizophrenia spectrum disorder (SSD) suffer from impaired cognitive functions. Previous studies in healthy individuals have shown that a single bout of physical exercise benefits cognitive functions. Such enhancements in cognitive function would be highly beneficial, particularly for patients with SSD, as cognitive abilities play a vital role in both mental and physical health.</p><p><strong>Methods: </strong>We examined the impact of a single bout of aerobic exercise on cognitive function in 25 patients with SSD and 24 healthy controls. Participants performed a single bout of aerobic exercise adjusted to their individual fitness level. Cognitive function was examined pre- and postexercise via oculomotor tasks consisting of saccadic (i.e., pro- and antisaccades) and smooth pursuit eye movements (SPEM). Furthermore, long-term physical fitness and movement activity were assessed through an anaerobic threshold testing and self-reports of physical activity.</p><p><strong>Results: </strong>As expected, SSD-patients showed higher antisaccade error rates and were impaired in both SPEM initiation and maintenance with higher disorganization levels being related to lower SPEM performance. Neither the patient nor control group benefited from a single bout of exercise in terms of improved saccade or SPEM performance. However, higher fitness levels and more extensive long-term movement activity were associated with lower antisaccade error rates in patients.</p><p><strong>Conclusion: </strong>These findings do not demonstrate a single bout postexercise benefit in cognition; however, results indicate an association between greater cognitive control and long-term movement activity and thus underscore the importance of conducting further investigations into long-term exercise interventions as a complementary therapeutic approach.</p>\",\"PeriodicalId\":11822,\"journal\":{\"name\":\"European Archives of Psychiatry and Clinical Neuroscience\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-09-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Archives of Psychiatry and Clinical Neuroscience\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00406-025-02101-0\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Archives of Psychiatry and Clinical Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00406-025-02101-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Cognitive control in schizophrenia spectrum disorders is associated with long-term movement activity rather than single-bout exercise.
Background: Patients with schizophrenia spectrum disorder (SSD) suffer from impaired cognitive functions. Previous studies in healthy individuals have shown that a single bout of physical exercise benefits cognitive functions. Such enhancements in cognitive function would be highly beneficial, particularly for patients with SSD, as cognitive abilities play a vital role in both mental and physical health.
Methods: We examined the impact of a single bout of aerobic exercise on cognitive function in 25 patients with SSD and 24 healthy controls. Participants performed a single bout of aerobic exercise adjusted to their individual fitness level. Cognitive function was examined pre- and postexercise via oculomotor tasks consisting of saccadic (i.e., pro- and antisaccades) and smooth pursuit eye movements (SPEM). Furthermore, long-term physical fitness and movement activity were assessed through an anaerobic threshold testing and self-reports of physical activity.
Results: As expected, SSD-patients showed higher antisaccade error rates and were impaired in both SPEM initiation and maintenance with higher disorganization levels being related to lower SPEM performance. Neither the patient nor control group benefited from a single bout of exercise in terms of improved saccade or SPEM performance. However, higher fitness levels and more extensive long-term movement activity were associated with lower antisaccade error rates in patients.
Conclusion: These findings do not demonstrate a single bout postexercise benefit in cognition; however, results indicate an association between greater cognitive control and long-term movement activity and thus underscore the importance of conducting further investigations into long-term exercise interventions as a complementary therapeutic approach.
期刊介绍:
The original papers published in the European Archives of Psychiatry and Clinical Neuroscience deal with all aspects of psychiatry and related clinical neuroscience.
Clinical psychiatry, psychopathology, epidemiology as well as brain imaging, neuropathological, neurophysiological, neurochemical and moleculargenetic studies of psychiatric disorders are among the topics covered.
Thus both the clinician and the neuroscientist are provided with a handy source of information on important scientific developments.