Pietro Ferrara , Margherita Zona , Ida Giardino , Francesca Scaltrito , Clara Pettoello-Mantovani , Ignazio Cammisa
{"title":"战争无声的创伤:对冲突地区儿童的身心影响和国际法律影响","authors":"Pietro Ferrara , Margherita Zona , Ida Giardino , Francesca Scaltrito , Clara Pettoello-Mantovani , Ignazio Cammisa","doi":"10.1016/j.gpeds.2025.100287","DOIUrl":null,"url":null,"abstract":"<div><div>Children exposed to war confront a distinct array of adversities that extend far beyond the immediate threats of violence and displacement. While the direct consequences—such as physical harm, the loss of loved ones, and the destruction of homes—are profoundly distressing, the more insidious and enduring damage often stems from the disruption of critical developmental processes. Armed conflict undermines the foundational elements required for healthy childhood development, including emotional security, consistent caregiving, education, accessible healthcare, stable social networks, and physical safety. The psychological impact of living in, or fleeing from, conflict zones infiltrates all aspects of a child's life. The breakdown of community infrastructure, forced displacement, and prolonged uncertainty severely limit opportunities for peer interaction, structured play, and social learning—experiences that are vital for shaping self-concept, empathy, and emotional regulation. In environments where fear, mistrust, and violence become normalized, children may struggle to form secure attachments or to envision a hopeful future. It is widely recognized that environmental and contextual factors exert a profound influence on children's developmental trajectories, encompassing cognitive, emotional, and physical domains. Research consistently highlights the role of neighborhood safety, access to healthcare and education, and socioeconomic stability in shaping developmental outcomes. At the neurobiological level, chronic exposure to stress activates regulatory systems such as the hypothalamic–pituitary–adrenal (HPA) axis, which, when persistently engaged, can interfere with brain maturation. This dysregulation is often associated with impairments in memory, attention, language acquisition, and executive functioning, and with increased susceptibility to internalizing disorders such as post-traumatic stress disorder (PTSD), anxiety, depression, and attachment-related difficulties.</div><div>Physiologically, prolonged stress can weaken immune function, disturb sleep patterns, hinder somatic growth, and elevate the risk of both acute health problems and chronic diseases. The pervasive and multi-dimensional impact of war on children calls not only for academic inquiry but also for immediate ethical and policy responses. This article emphasizes that a nuanced understanding of trauma's effects across developmental systems is critical to inform targeted, trauma-responsive interventions.</div><div>The aim is to raise attention on the importance of establishing effective strategies, which must prioritize not only the treatment of individual symptoms but also broader efforts aimed at prevention and systemic recovery, thereby fostering resilience and contributing to the long-term rehabilitation of communities affected by conflict.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"14 ","pages":"Article 100287"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The silent wounds of war: Psycho-physical impacts and international legal implications for children in conflict zones\",\"authors\":\"Pietro Ferrara , Margherita Zona , Ida Giardino , Francesca Scaltrito , Clara Pettoello-Mantovani , Ignazio Cammisa\",\"doi\":\"10.1016/j.gpeds.2025.100287\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Children exposed to war confront a distinct array of adversities that extend far beyond the immediate threats of violence and displacement. While the direct consequences—such as physical harm, the loss of loved ones, and the destruction of homes—are profoundly distressing, the more insidious and enduring damage often stems from the disruption of critical developmental processes. Armed conflict undermines the foundational elements required for healthy childhood development, including emotional security, consistent caregiving, education, accessible healthcare, stable social networks, and physical safety. The psychological impact of living in, or fleeing from, conflict zones infiltrates all aspects of a child's life. The breakdown of community infrastructure, forced displacement, and prolonged uncertainty severely limit opportunities for peer interaction, structured play, and social learning—experiences that are vital for shaping self-concept, empathy, and emotional regulation. In environments where fear, mistrust, and violence become normalized, children may struggle to form secure attachments or to envision a hopeful future. It is widely recognized that environmental and contextual factors exert a profound influence on children's developmental trajectories, encompassing cognitive, emotional, and physical domains. Research consistently highlights the role of neighborhood safety, access to healthcare and education, and socioeconomic stability in shaping developmental outcomes. At the neurobiological level, chronic exposure to stress activates regulatory systems such as the hypothalamic–pituitary–adrenal (HPA) axis, which, when persistently engaged, can interfere with brain maturation. This dysregulation is often associated with impairments in memory, attention, language acquisition, and executive functioning, and with increased susceptibility to internalizing disorders such as post-traumatic stress disorder (PTSD), anxiety, depression, and attachment-related difficulties.</div><div>Physiologically, prolonged stress can weaken immune function, disturb sleep patterns, hinder somatic growth, and elevate the risk of both acute health problems and chronic diseases. The pervasive and multi-dimensional impact of war on children calls not only for academic inquiry but also for immediate ethical and policy responses. This article emphasizes that a nuanced understanding of trauma's effects across developmental systems is critical to inform targeted, trauma-responsive interventions.</div><div>The aim is to raise attention on the importance of establishing effective strategies, which must prioritize not only the treatment of individual symptoms but also broader efforts aimed at prevention and systemic recovery, thereby fostering resilience and contributing to the long-term rehabilitation of communities affected by conflict.</div></div>\",\"PeriodicalId\":73173,\"journal\":{\"name\":\"Global pediatrics\",\"volume\":\"14 \",\"pages\":\"Article 100287\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Global pediatrics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2667009725000454\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global pediatrics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667009725000454","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The silent wounds of war: Psycho-physical impacts and international legal implications for children in conflict zones
Children exposed to war confront a distinct array of adversities that extend far beyond the immediate threats of violence and displacement. While the direct consequences—such as physical harm, the loss of loved ones, and the destruction of homes—are profoundly distressing, the more insidious and enduring damage often stems from the disruption of critical developmental processes. Armed conflict undermines the foundational elements required for healthy childhood development, including emotional security, consistent caregiving, education, accessible healthcare, stable social networks, and physical safety. The psychological impact of living in, or fleeing from, conflict zones infiltrates all aspects of a child's life. The breakdown of community infrastructure, forced displacement, and prolonged uncertainty severely limit opportunities for peer interaction, structured play, and social learning—experiences that are vital for shaping self-concept, empathy, and emotional regulation. In environments where fear, mistrust, and violence become normalized, children may struggle to form secure attachments or to envision a hopeful future. It is widely recognized that environmental and contextual factors exert a profound influence on children's developmental trajectories, encompassing cognitive, emotional, and physical domains. Research consistently highlights the role of neighborhood safety, access to healthcare and education, and socioeconomic stability in shaping developmental outcomes. At the neurobiological level, chronic exposure to stress activates regulatory systems such as the hypothalamic–pituitary–adrenal (HPA) axis, which, when persistently engaged, can interfere with brain maturation. This dysregulation is often associated with impairments in memory, attention, language acquisition, and executive functioning, and with increased susceptibility to internalizing disorders such as post-traumatic stress disorder (PTSD), anxiety, depression, and attachment-related difficulties.
Physiologically, prolonged stress can weaken immune function, disturb sleep patterns, hinder somatic growth, and elevate the risk of both acute health problems and chronic diseases. The pervasive and multi-dimensional impact of war on children calls not only for academic inquiry but also for immediate ethical and policy responses. This article emphasizes that a nuanced understanding of trauma's effects across developmental systems is critical to inform targeted, trauma-responsive interventions.
The aim is to raise attention on the importance of establishing effective strategies, which must prioritize not only the treatment of individual symptoms but also broader efforts aimed at prevention and systemic recovery, thereby fostering resilience and contributing to the long-term rehabilitation of communities affected by conflict.