糖尿病神经病变患者压疮风险的管理：临床常规的机械生物学观点。

IF 1.7 4区医学 Q3 DERMATOLOGY

Journal of wound care Pub Date : 2025-09-02 DOI:10.12968/jowc.2025.0313

Bérengère Fromy, Antoine Perrier

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引用次数: 0

摘要

本文旨在强调糖尿病神经病变足溃疡风险的机械生物学决定因素。这种情况改变了感觉运动控制，减弱了压力引起的血管舒张，使软组织暴露于持续的劳损和缺血，即使没有明显的畸形。本文以实验力学生物学和影像学病例研究为基础，对糖尿病神经病变的临床研究进行综述。结论溃疡预防应将血管力学生物学和生物力学评估纳入个性化卸载策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Managing pressure ulcer risk in patients with diabetic neuropathy: a mechanobiological perspective for clinical routine.

This article aims to highlight the mechanobiological determinants of foot ulcer risk in diabetic neuropathy. This condition alters sensorimotor control and blunts pressure-induced vasodilation, exposing soft tissues to sustained strain and ischaemia, even without visible deformity. This article presents a narrative clinical review supported by experimental mechanobiology and imaging case studies on diabetic neuropathy. It concludes that ulcer prevention should integrate vascular mechanobiology and biomechanic evaluation into personalised offloading strategies.

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来源期刊

Journal of wound care DERMATOLOGY-

CiteScore

2.90

自引率

10.50%

发文量

215

期刊介绍： Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice. In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers. Specifically, JWC publishes: High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments Clinical case studies providing information on how to deal with complex wounds Comprehensive literature reviews on current concepts and practice, including cost-effectiveness Updates on the activities of wound care societies around the world.