均相碱金属催化不饱和含n有机化合物的转移加氢反应

IF 3.9 3区 化学 Q2 CHEMISTRY, PHYSICAL
ChemCatChem Pub Date : 2025-08-05 DOI:10.1002/cctc.202500702
Ainur Slamova, Dr. Kristina A. Gudun, Dr. Andrey Y. Khalimon
{"title":"均相碱金属催化不饱和含n有机化合物的转移加氢反应","authors":"Ainur Slamova,&nbsp;Dr. Kristina A. Gudun,&nbsp;Dr. Andrey Y. Khalimon","doi":"10.1002/cctc.202500702","DOIUrl":null,"url":null,"abstract":"<p>Owing to the synthetic availability of imines, N-heteroarenes, nitriles, carboxamides, and nitroarenes, their catalytic hydrogenation is considered an attractive and atom-economical route to a diversity of amines, which find widespread applications specialty chemical industries. Although catalytic hydrogenation of unsaturated N-containing organic compounds with compressed H<sub>2</sub> gas is well-established, such transformations require expensive high-pressure equipment and have associated H<sub>2</sub> handling risks. In contrast, transfer hydrogenation protocols utilize nongaseous hydrogen sources, offering significant advantages in the operational cost and safety of transformations. Whereas many economical nonprecious metal catalysts have been described for efficient transfer hydrogenation of aldehydes and ketones, similar systems for selective transfer hydrogenation of unsaturated nitrogen-containing organic compounds have been developed relatively recently. This review aims to highlight current advances and challenges of base-metal-catalyzed (i.e., Mn, Fe, Co, Ni, and Cu) transfer hydrogenation of imines, N-heteroarenes, nitriles, nitro compounds, as well as carboxamides and related molecules to the corresponding amines. Mechanistic aspects of catalytic reactions, the substrate scope, and selectivity of the transformations are also discussed.</p>","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":"17 17","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Homogeneous Base-Metal-Catalyzed Transfer Hydrogenation of Unsaturated N-Containing Organic Compounds\",\"authors\":\"Ainur Slamova,&nbsp;Dr. Kristina A. Gudun,&nbsp;Dr. Andrey Y. Khalimon\",\"doi\":\"10.1002/cctc.202500702\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Owing to the synthetic availability of imines, N-heteroarenes, nitriles, carboxamides, and nitroarenes, their catalytic hydrogenation is considered an attractive and atom-economical route to a diversity of amines, which find widespread applications specialty chemical industries. Although catalytic hydrogenation of unsaturated N-containing organic compounds with compressed H<sub>2</sub> gas is well-established, such transformations require expensive high-pressure equipment and have associated H<sub>2</sub> handling risks. In contrast, transfer hydrogenation protocols utilize nongaseous hydrogen sources, offering significant advantages in the operational cost and safety of transformations. Whereas many economical nonprecious metal catalysts have been described for efficient transfer hydrogenation of aldehydes and ketones, similar systems for selective transfer hydrogenation of unsaturated nitrogen-containing organic compounds have been developed relatively recently. This review aims to highlight current advances and challenges of base-metal-catalyzed (i.e., Mn, Fe, Co, Ni, and Cu) transfer hydrogenation of imines, N-heteroarenes, nitriles, nitro compounds, as well as carboxamides and related molecules to the corresponding amines. Mechanistic aspects of catalytic reactions, the substrate scope, and selectivity of the transformations are also discussed.</p>\",\"PeriodicalId\":141,\"journal\":{\"name\":\"ChemCatChem\",\"volume\":\"17 17\",\"pages\":\"\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-08-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ChemCatChem\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cctc.202500702\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ChemCatChem","FirstCategoryId":"92","ListUrlMain":"https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cctc.202500702","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0

摘要

由于亚胺、n -杂芳烃、腈、羧酰胺和硝基芳烃的可合成性,它们的催化加氢被认为是一种有吸引力的、原子经济的途径,可以合成多种胺,这些胺在特种化学工业中得到广泛应用。虽然用压缩氢气催化含n的不饱和有机化合物加氢已经很成熟,但这种转化需要昂贵的高压设备,并且存在相关的氢气处理风险。相比之下,转移氢化方案利用非质氢源,在操作成本和转换安全性方面具有显着优势。虽然许多经济的非贵金属催化剂已经被描述为有效的醛和酮的转移加氢,但不饱和含氮有机化合物的选择性转移加氢的类似系统最近才被开发出来。本文综述了以贱金属为催化剂(Mn、Fe、Co、Ni和Cu)催化亚胺、n -杂芳烃、腈、硝基化合物以及羧胺及其相关分子向相应胺转移加氢的研究进展和面临的挑战。还讨论了催化反应的机理、底物范围和转化的选择性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Homogeneous Base-Metal-Catalyzed Transfer Hydrogenation of Unsaturated N-Containing Organic Compounds

Homogeneous Base-Metal-Catalyzed Transfer Hydrogenation of Unsaturated N-Containing Organic Compounds

Homogeneous Base-Metal-Catalyzed Transfer Hydrogenation of Unsaturated N-Containing Organic Compounds

Homogeneous Base-Metal-Catalyzed Transfer Hydrogenation of Unsaturated N-Containing Organic Compounds

Owing to the synthetic availability of imines, N-heteroarenes, nitriles, carboxamides, and nitroarenes, their catalytic hydrogenation is considered an attractive and atom-economical route to a diversity of amines, which find widespread applications specialty chemical industries. Although catalytic hydrogenation of unsaturated N-containing organic compounds with compressed H2 gas is well-established, such transformations require expensive high-pressure equipment and have associated H2 handling risks. In contrast, transfer hydrogenation protocols utilize nongaseous hydrogen sources, offering significant advantages in the operational cost and safety of transformations. Whereas many economical nonprecious metal catalysts have been described for efficient transfer hydrogenation of aldehydes and ketones, similar systems for selective transfer hydrogenation of unsaturated nitrogen-containing organic compounds have been developed relatively recently. This review aims to highlight current advances and challenges of base-metal-catalyzed (i.e., Mn, Fe, Co, Ni, and Cu) transfer hydrogenation of imines, N-heteroarenes, nitriles, nitro compounds, as well as carboxamides and related molecules to the corresponding amines. Mechanistic aspects of catalytic reactions, the substrate scope, and selectivity of the transformations are also discussed.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
ChemCatChem
ChemCatChem 化学-物理化学
CiteScore
8.10
自引率
4.40%
发文量
511
审稿时长
1.3 months
期刊介绍: With an impact factor of 4.495 (2018), ChemCatChem is one of the premier journals in the field of catalysis. The journal provides primary research papers and critical secondary information on heterogeneous, homogeneous and bio- and nanocatalysis. The journal is well placed to strengthen cross-communication within between these communities. Its authors and readers come from academia, the chemical industry, and government laboratories across the world. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies, and is supported by the German Catalysis Society.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信