{"title":"模拟上尿路上皮癌的子宫内膜样癌转移","authors":"Yuji Fujizuka , Shugo Harashima , Yoshiyuki Miyazawa , Seiji Arai , Nozomi Nakajima , Mai Onose , Sho Watanuki , Takanori Shimizu , Yoshitaka Sekine , Hidekazu Koike , Hayato Ikota , Kazuhiro Suzuki","doi":"10.1016/j.eucr.2025.103195","DOIUrl":null,"url":null,"abstract":"<div><div>Accurate diagnosis of upper-tract urothelial carcinoma is difficult when urine cytology and ureteroscopy are inconclusive. A 59-year-old woman had undergone total hysterectomy for uterine endometrioid carcinoma 5 years earlier. Follow-up computed tomography demonstrated left hydronephrosis and an enhancing mass in the ureter. Urine cytology was negative, but ureteroscopic biopsies revealed malignant cells that were potentially urothelial carcinoma. The patient received left nephroureterectomy, but histopathology unexpectedly showed metastatic uterine endometrioid carcinoma. This case highlights that metastatic relapse of uterine carcinoma can mimic ureteral cancer on imaging. When cytology and biopsy are inconclusive, prior malignancies should remain in the differential diagnosis.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"63 ","pages":"Article 103195"},"PeriodicalIF":0.4000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metastasis of uterine endometrioid carcinoma mimicking upper tract urothelial carcinoma\",\"authors\":\"Yuji Fujizuka , Shugo Harashima , Yoshiyuki Miyazawa , Seiji Arai , Nozomi Nakajima , Mai Onose , Sho Watanuki , Takanori Shimizu , Yoshitaka Sekine , Hidekazu Koike , Hayato Ikota , Kazuhiro Suzuki\",\"doi\":\"10.1016/j.eucr.2025.103195\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Accurate diagnosis of upper-tract urothelial carcinoma is difficult when urine cytology and ureteroscopy are inconclusive. A 59-year-old woman had undergone total hysterectomy for uterine endometrioid carcinoma 5 years earlier. Follow-up computed tomography demonstrated left hydronephrosis and an enhancing mass in the ureter. Urine cytology was negative, but ureteroscopic biopsies revealed malignant cells that were potentially urothelial carcinoma. The patient received left nephroureterectomy, but histopathology unexpectedly showed metastatic uterine endometrioid carcinoma. This case highlights that metastatic relapse of uterine carcinoma can mimic ureteral cancer on imaging. When cytology and biopsy are inconclusive, prior malignancies should remain in the differential diagnosis.</div></div>\",\"PeriodicalId\":38188,\"journal\":{\"name\":\"Urology Case Reports\",\"volume\":\"63 \",\"pages\":\"Article 103195\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214442025002669\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214442025002669","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Metastasis of uterine endometrioid carcinoma mimicking upper tract urothelial carcinoma
Accurate diagnosis of upper-tract urothelial carcinoma is difficult when urine cytology and ureteroscopy are inconclusive. A 59-year-old woman had undergone total hysterectomy for uterine endometrioid carcinoma 5 years earlier. Follow-up computed tomography demonstrated left hydronephrosis and an enhancing mass in the ureter. Urine cytology was negative, but ureteroscopic biopsies revealed malignant cells that were potentially urothelial carcinoma. The patient received left nephroureterectomy, but histopathology unexpectedly showed metastatic uterine endometrioid carcinoma. This case highlights that metastatic relapse of uterine carcinoma can mimic ureteral cancer on imaging. When cytology and biopsy are inconclusive, prior malignancies should remain in the differential diagnosis.
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