循环CLA+记忆T细胞在皮肤病中的作用

JID innovations : skin science from molecules to population health Pub Date : 2025-08-05 DOI:10.1016/j.xjidi.2025.100403

Tali Czarnowicki , Lea Tordjman , Irene García-Jiménez , Luis F. Santamaria-Babí

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引用次数: 0

摘要

循环皮肤淋巴细胞相关抗原阳性T细胞构成记忆T细胞的一个亚群，具有独特的表型、效应功能和治疗相关性，因为它们反映了皮肤免疫系统的区域功能。这些细胞参与多种皮肤疾病的病理机制。这篇综述为这些细胞带来了最新的翻译见解，并确定了该领域未来研究的关键问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Circulating CLA+ Memory T Cells in Skin Diseases: A Translational Perspective

Circulating cutaneous lymphocyte-associated antigen–positive T cells constitute a subset of memory T cells with a unique phenotype, effector function, and therapeutic relevance because they reflect the regional functions of the cutaneous immune system. These cells are involved in the pathological mechanisms of diverse cutaneous diseases. This review brings updated translational insights into these cells and identifies key questions for future research in the field.

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来源期刊

JID innovations : skin science from molecules to population health Dermatology

CiteScore

4.00

自引率

0.00%

发文量

审稿时长

8 weeks