用于敏感生物传感的水不敏感下移纳米颗粒

IF 23.4 Q1 OPTICS

Light-Science & Applications Pub Date : 2025-09-05 DOI:10.1038/s41377-025-01976-x

Jiang Ming, Sikun Hu, Fan Zhang

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引用次数: 0

摘要

传统的光学探针在水介质中存在信号退化的问题，阻碍了灵敏的生物检测。为了克服这个问题，新开发的水不敏感下移纳米颗粒（WINPs）在NIR-I窗口中具有优越的光物理性质，包括高量子产率和可忽略的热效应，允许在低激发功率下产生稳定的高对比度信号。这一优势有助于在不透明的生物基质（如禽类拭子）中进行高灵敏度禽流感病毒（AIV）检测的低功率侧流试验，减轻了依赖于可见范围信号的干扰问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Water-insensitive down-shifting nanoparticles for sensitive biosensing

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Water-insensitive down-shifting nanoparticles for sensitive biosensing

Conventional optical probes suffer from signal degradation in aqueous media, hindering sensitive biodetection. To overcome this, newly developed water-insensitive down-shifting nanoparticles (WINPs) possess superior photophysical properties in the NIR-I window, including high quantum yield and negligible thermal effects, permitting stable, high-contrast signal generation under low excitation power. This advantage facilitated a low-power lateral flow assay capable of highly sensitive avian influenza virus (AIV) detection in the opaque biological matrices (such as avian swabs), mitigating interference issues relying on visible-range signals.

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来源期刊

Light-Science & Applications 数理科学, 物理学I, 光学, 凝聚态物性 II ：电子结构、电学、磁学和光学性质, 无机非金属材料, 无机非金属类光电信息与功能材料, 工程与材料, 信息科学, 光学和光电子学, 光学和光电子材料, 非线性光学与量子光学

自引率

0.00%

发文量

803

审稿时长

2.1 months