[中国口腔遗传疾病综述]。

Q4 Medicine
J Liang, Z Bian
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引用次数: 0

摘要

本文对国内口腔遗传疾病的研究进展和取得的成果进行了综述。自20世纪50年代以来,中国学者从流行病学调查发展到阐明分子机制和功能基因组学,标志着从宏观观察到微观分析的转变。研究主要集中在三大类:唇腭裂、牙齿发育异常和罕见的遗传性口腔疾病。几个关键的致病基因已被确定,并阐明了它们的分子机制和表型特征。本文总结了代表性研究成果,分析了当前面临的挑战,并提出了未来的研究方向,旨在为推进中国口腔遗传学领域的基础研究和临床转化提供理论支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Review of oral genetic diseases in China].

This study provides a comprehensive review of the development and achievements in the field of oral genetic disorders research in China. Since the 1950s, Chinese scholars have progressed from epidemiological surveys to the elucidation of molecular mechanisms and functional genomics, marking a transition from macro-level observations to micro-level analyses. The research focuses on three major categories: cleft lip and palate, dental developmental anomalies, and rare hereditary oral diseases. Several critical pathogenic genes have been identified, and their molecular mechanisms and phenotypic characteristics elucidated. This paper summarizes representative findings, analyzes current challenges, and outlines future research directions, aiming to provide theoretical support for advancing both basic research and clinical translation in the field of oral genetics in China.

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来源期刊
中华口腔医学杂志
中华口腔医学杂志 Medicine-Medicine (all)
CiteScore
0.90
自引率
0.00%
发文量
9692
期刊介绍: Founded in August 1953, Chinese Journal of Stomatology is a monthly academic journal of stomatology published publicly at home and abroad, sponsored by the Chinese Medical Association and co-sponsored by the Chinese Stomatology Association. It mainly reports the leading scientific research results and clinical diagnosis and treatment experience in the field of oral medicine, as well as the basic theoretical research that has a guiding role in oral clinical practice and is closely combined with oral clinical practice. Chinese Journal of Over the years, Stomatology has been published in Medline, Scopus database, Toxicology Abstracts Database, Chemical Abstracts Database, American Cancer database, Russian Abstracts database, China Core Journal of Science and Technology, Peking University Core Journal, CSCD and other more than 20 important journals at home and abroad Physical medicine database and retrieval system included.
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