医疗补助处方上限政策与阿片类药物使用障碍患者的急性护理使用和死亡率

IF 3.6 2区 医学 Q1 PSYCHIATRY
Patience M. Dow , Christopher M. Santostefano , Landon D. Hughes , Elizabeth G. Stettenbauer , Theresa I. Shireman , Julie M. Donohue , Lisa Peterson , Jaclyn M.W. Hughto
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引用次数: 0

摘要

背景:12个州的医疗补助计划限制了每月覆盖的处方数量。这样的上限政策可能会迫使参保人放弃对健康有重要影响的基本药物。我们的目的是确定上限政策对阿片类药物使用障碍(OUD)患者急性护理使用和全因死亡率的影响。方法使用2016-2019年T-MSIS分析文件,我们将12个有上限政策的州和26个没有上限政策的州的入组者与OUD进行倾向评分匹配。12个月内测量的结果包括急诊科(ED)就诊、住院和全因死亡率,并通过广义线性回归模型进行分析。我们通过使用OUD药物进行亚组分析,并进行合并症水平和敏感性分析,以检验上限政策特征的作用。结果在限制州和非限制州,急诊科就诊的调整风险分别为64.0%和62.5%,住院治疗的调整风险分别为27.6%和27.5%,死亡率调整风险分别为3.2%和2.7%。调整后,cap州的住院风险高于非cap州(RR=1.89, 99.5% CI:1.13,3.16),而急诊科就诊和死亡率没有差异。在亚组中,cap状态基本上没有结果差异。严格的处方限制允许每月3-4次处方(RR=1.90, 95% CI:1.09,3.30)和缺乏mod豁免(RR=2.23, 95% CI:1.32,3.78)与非上限国家的住院风险增加相关。结论:医疗补助处方上限政策与住院风险增加有关,但在ED使用和全因死亡率方面没有差异。上限政策可能会损害OUD患者的健康,并可能对国家遏制医疗补助支出的努力产生反作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Medicaid prescription cap policies and acute care use and mortality among enrollees with opioid use disorder

Background

Twelve state Medicaid programs limit the monthly number of covered prescriptions. Such cap policies may force enrollees to forego essential medications with important health consequences. We aimed to determine the impact of cap policies on acute care use and all-cause mortality among enrollees with opioid use disorder (OUD).

Methods

Using 2016–2019 T-MSIS Analytical Files, we propensity-score matched enrollees with OUD in 12 states with cap policies and 26 states without cap policies. Outcomes measured over 12 months included emergency department (ED) visits, hospitalization, and all-cause mortality and were analyzed via generalized linear regression models. We conducted subgroup analyses by use of medications for OUD (MOUD) and comorbidity level and sensitivity analyses to examine the role of cap policy characteristics.

Results

Unadjusted risks were 64.0 % vs. 62.5 % for ED visits, 27.6 % vs. 27.5 % for hospitalizations, and 3.2 % vs. 2.7 % for mortality in cap states and non-cap states, respectively. After adjustment, hospitalization risk was higher (RR=1.89, 99.5 %CI:1.13,3.16) in cap states than non-cap states whereas ED visits and mortality did not differ. There were largely no outcome differences by cap status in subgroups. Strict prescription limits allowing 3–4 prescriptions monthly (RR=1.90, 95 %CI:1.09,3.30) and lack of MOUD exemptions (RR=2.23, 95 %CI:1.32,3.78) were associated with increased hospitalization risk relative to non-cap states.

Conclusions

Medicaid prescription cap policies were associated with increased hospitalization risk, but there were no differences in ED use or all-cause mortality. Cap policies may undermine the health of individuals with OUD and could be counterproductive to state efforts to curb Medicaid spending.
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来源期刊
Drug and alcohol dependence
Drug and alcohol dependence 医学-精神病学
CiteScore
7.40
自引率
7.10%
发文量
409
审稿时长
41 days
期刊介绍: Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.
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