病因是选择血管内或开放治疗急性肠系膜缺血的一个因素。

IF 0.7
Tejas S Nandurkar, Olivia H Millay, Eric D Endean
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引用次数: 0

摘要

背景血管内治疗在AMI患者中的作用仍存在争议。本研究旨在比较AMI的开放治疗和血管内治疗。方法对2010 - 2022年间所有AMI患者进行分析。记录患者人口统计、基线实验室研究、住院时间(LOS)和结果。定量数据采用学生t检验,定性数据采用费雪精确检验。结果65例急性心肌梗死患者:47例采用开腹手术;18采用血管内技术。血管内组18例患者中,8例(45%)行开腹/腹腔镜手术;4例(22%)需要肠切除术。经血管内入路治疗的患者男性(87% vs 45%, P = 0.025)、血栓形成(78% vs 55%, P = 0.005)、其他血管疾病发生率较低(56% vs 87%, P = 0.015)、初始白细胞较低(11.9±3.9 vs 18.5±8.4,P = 0.0017)。血管内组ICU LOS较短(5.5±5.7 vs 13.5±13.8,P = 0.025)。与开放组相比,血管内组有减少肠切除术的趋势[4(22%)比19 (40%),P = .25]。与开放组相比,血管内组的死亡率有降低的趋势(22% vs 40%, P = 0.25)。在死亡的23例患者中,16例(70%)与肠缺血直接相关,5例(22%)与心脏直接相关,2例(9%)与中风直接相关。结论血管内治疗AMI具有较低的死亡率和住院时间。当选择血管内治疗还是开放治疗时,肠的状态应该是一个重要的初始决定因素。我们建议,如果栓塞性疾病患者的血管内治疗不能迅速恢复肠系膜血流,则应考虑潜在的病因(血栓形成vs栓塞),并考虑低阈值转换为开放手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Etiology is a Factor when Choosing Endovascular or Open Treatment for Acute Mesenteric Ischemia.

BackgroundThe role of endovascular therapy for patients presenting with AMI continues to be debated. This study was undertaken to compare open and endovascular treatment of AMI.MethodsAll patients who presented with AMI between 2010 and 2022 were identified. Patient demographics, baseline laboratory studies, length of stay (LOS), and outcomes were recorded. Student's t-test was used for quantitative data and Fisher's exact test for qualitative data.ResultsSixty-five patients were treated for AMI: 47 with an open procedure; 18 with endovascular techniques. Of the 18 patients in the endovascular group, 8 (45%) underwent laparotomy/laparoscopy; four (22%) requiring bowel resection. Patients treated with an endovascular approach were more likely to be male (87% vs 45%, P = .025), be caused by thrombosis (78% vs 55%, P = .005), have lower incidence of other vascular disease (56% vs 87%, P = .015) and have a lower initial WBC (11.9 ± 3.9 vs 18.5 ± 8.4, P = .0017). There was shorter ICU LOS in the endovascular group (5.5 ± 5.7 vs 13.5 ± 13.8, P = .025). A trend for decreased bowel resection was seen in the endovascular group compared the open group [4 (22%) vs 19 (40%), P = .25]. A trend for lower mortality was seen in the endovascular group compared to the open group (22% vs 40%, P = .25). In the 23 patients that died, the cause of death was directly related to bowel ischemia in 16 (70%), cardiac in 5 (22%) and stroke in 2 (9%).ConclusionEndovascular treatment of AMI has potentially lower mortality and lengths of stay. When choosing endovascular vs open treatment, the status of the bowel should be an important initial determinate. We recommend that the underlying etiology (thrombosis vs embolic) also be a consideration with a low threshold for conversion to an open procedure if endovascular treatment does not rapidly restore mesenteric flow in patients with embolic disease.

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