{"title":"血管内光学相干断层扫描对冠心病患者经皮冠状动脉介入治疗的预后价值。","authors":"Zhengya Fang, Suwen Zhu, Shaodong Zhang, Yingchun Liu, Yueyun Shen, Ye Zhang","doi":"10.1002/jbio.202500184","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>We aimed to ascertain the predictive value of intravascular optical coherence tomography (OCT) in the prognosis of coronary heart disease (CHD) patients undergoing percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>Independent factors affecting major adverse cardiac events (MACE) and predictive efficacy of OCT parameters on MACE in CHD patients were analyzed.</p><p><strong>Results: </strong>Advanced age and large lipid arc degree were risk factors for MACE occurrence (OR > 1, p < 0.05), while thick fibrous cap thickness and high left ventricular ejection fraction were protective (OR < 1, p < 0.05). Fibrous cap thickness predicted MACE (AUC 0.765, 95% CI 0.690 ~ 0.840, cut-off 92 μm); lipid arc degree did as well (AUC 0.885, 95% CI 0.817 ~ 0.952, cut-off 214.5°).</p><p><strong>Conclusion: </strong>OCT supports interventional treatment in CHD patients, with fibrous cap thickness and lipid arc degree demonstrating some prognostic predictive value post-PCI.</p>","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e202500184"},"PeriodicalIF":2.3000,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prognostic Value of Intravascular Optical Coherence Tomography in Patients With Coronary Heart Disease Undergoing Percutaneous Coronary Intervention.\",\"authors\":\"Zhengya Fang, Suwen Zhu, Shaodong Zhang, Yingchun Liu, Yueyun Shen, Ye Zhang\",\"doi\":\"10.1002/jbio.202500184\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>We aimed to ascertain the predictive value of intravascular optical coherence tomography (OCT) in the prognosis of coronary heart disease (CHD) patients undergoing percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>Independent factors affecting major adverse cardiac events (MACE) and predictive efficacy of OCT parameters on MACE in CHD patients were analyzed.</p><p><strong>Results: </strong>Advanced age and large lipid arc degree were risk factors for MACE occurrence (OR > 1, p < 0.05), while thick fibrous cap thickness and high left ventricular ejection fraction were protective (OR < 1, p < 0.05). Fibrous cap thickness predicted MACE (AUC 0.765, 95% CI 0.690 ~ 0.840, cut-off 92 μm); lipid arc degree did as well (AUC 0.885, 95% CI 0.817 ~ 0.952, cut-off 214.5°).</p><p><strong>Conclusion: </strong>OCT supports interventional treatment in CHD patients, with fibrous cap thickness and lipid arc degree demonstrating some prognostic predictive value post-PCI.</p>\",\"PeriodicalId\":94068,\"journal\":{\"name\":\"Journal of biophotonics\",\"volume\":\" \",\"pages\":\"e202500184\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-08-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of biophotonics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/jbio.202500184\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biophotonics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/jbio.202500184","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Prognostic Value of Intravascular Optical Coherence Tomography in Patients With Coronary Heart Disease Undergoing Percutaneous Coronary Intervention.
Objective: We aimed to ascertain the predictive value of intravascular optical coherence tomography (OCT) in the prognosis of coronary heart disease (CHD) patients undergoing percutaneous coronary intervention (PCI).
Methods: Independent factors affecting major adverse cardiac events (MACE) and predictive efficacy of OCT parameters on MACE in CHD patients were analyzed.
Results: Advanced age and large lipid arc degree were risk factors for MACE occurrence (OR > 1, p < 0.05), while thick fibrous cap thickness and high left ventricular ejection fraction were protective (OR < 1, p < 0.05). Fibrous cap thickness predicted MACE (AUC 0.765, 95% CI 0.690 ~ 0.840, cut-off 92 μm); lipid arc degree did as well (AUC 0.885, 95% CI 0.817 ~ 0.952, cut-off 214.5°).
Conclusion: OCT supports interventional treatment in CHD patients, with fibrous cap thickness and lipid arc degree demonstrating some prognostic predictive value post-PCI.
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