P C Guidone, Roberta Seccia, L A Fabrocini, G Troiano, G Maffei, Maria Carmela Pedicillo, Giuseppe Pannone, Lorenzo Lo Muzio, Rosanna Zamparese, Giorgio Mori, Ilenia Sara De Stefano
{"title":"新生儿先天性颗粒细胞脓包1例，诊断、治疗及预后回顾。","authors":"P C Guidone, Roberta Seccia, L A Fabrocini, G Troiano, G Maffei, Maria Carmela Pedicillo, Giuseppe Pannone, Lorenzo Lo Muzio, Rosanna Zamparese, Giorgio Mori, Ilenia Sara De Stefano","doi":"10.3389/froh.2025.1548291","DOIUrl":null,"url":null,"abstract":"<p><p>Congenital granular cell epulis (CGCE) is a rare benign tumor typically presenting at birth and most commonly located on the maxillary alveolar ridge.</p><p><strong>Case presentation: </strong>We report the case of a five-day-old female with a smooth, multilobulated mass on the right maxillary alveolar ridge causing feeding difficulties. Surgical excision was performed under sedation. Histological and immunohistochemical analysis confirmed the diagnosis of CGCE. No recurrence was observed at one-month follow-up.</p><p><strong>Conclusion: </strong>Early diagnosis and surgical treatment of CGCE are essential to avoid functional impairment. The prognosis is excellent following complete excision.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1548291"},"PeriodicalIF":3.1000,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12375573/pdf/","citationCount":"0","resultStr":"{\"title\":\"Congenital granular cell epulis in a neonate: a case report and review of diagnosis, treatment, and prognosis.\",\"authors\":\"P C Guidone, Roberta Seccia, L A Fabrocini, G Troiano, G Maffei, Maria Carmela Pedicillo, Giuseppe Pannone, Lorenzo Lo Muzio, Rosanna Zamparese, Giorgio Mori, Ilenia Sara De Stefano\",\"doi\":\"10.3389/froh.2025.1548291\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Congenital granular cell epulis (CGCE) is a rare benign tumor typically presenting at birth and most commonly located on the maxillary alveolar ridge.</p><p><strong>Case presentation: </strong>We report the case of a five-day-old female with a smooth, multilobulated mass on the right maxillary alveolar ridge causing feeding difficulties. Surgical excision was performed under sedation. Histological and immunohistochemical analysis confirmed the diagnosis of CGCE. No recurrence was observed at one-month follow-up.</p><p><strong>Conclusion: </strong>Early diagnosis and surgical treatment of CGCE are essential to avoid functional impairment. The prognosis is excellent following complete excision.</p>\",\"PeriodicalId\":94016,\"journal\":{\"name\":\"Frontiers in oral health\",\"volume\":\"6 \",\"pages\":\"1548291\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-08-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12375573/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in oral health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3389/froh.2025.1548291\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in oral health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3389/froh.2025.1548291","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Congenital granular cell epulis in a neonate: a case report and review of diagnosis, treatment, and prognosis.
Congenital granular cell epulis (CGCE) is a rare benign tumor typically presenting at birth and most commonly located on the maxillary alveolar ridge.
Case presentation: We report the case of a five-day-old female with a smooth, multilobulated mass on the right maxillary alveolar ridge causing feeding difficulties. Surgical excision was performed under sedation. Histological and immunohistochemical analysis confirmed the diagnosis of CGCE. No recurrence was observed at one-month follow-up.
Conclusion: Early diagnosis and surgical treatment of CGCE are essential to avoid functional impairment. The prognosis is excellent following complete excision.
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