[污水处理厂职业活动引起的钩端螺旋体病——一种公认的职业病病例报告]。

IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-09-01 Epub Date: 2025-08-29 DOI:10.1055/a-2612-3357
Ludwig Frei-Stuber, Dennis Nowak
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引用次数: 0

摘要

患者(男性,两份专家报告:61岁和63岁)出现流感样感染症状,病情迅速恶化,认知能力出现不适。他在一家污水处理厂的市政建筑场地工作了大约24年。急性肾功能不全(肌酐9.7 mg/dl),抗钩端螺旋体IgM抗体升高,PCR检测钩端螺旋体DNA升高。未加对比剂的CT未见相关异常。脓毒症合并多器官功能衰竭,包括2型心肌梗死和急性肾功能衰竭,在钩端螺旋体病的背景下被诊断。给予哌拉西林/他唑巴坦、克拉霉素、美罗培南等抗生素治疗。对于急性肾功能衰竭患者,临时血液透析可显著改善肾功能。经评估后,根据《职业病条例》附录1,钩端螺旋体病被确认为第3102号职业病。医生应该记录工作经历,如果有合理的怀疑,在法律上有义务报告疑似职业病。充分的职业安全可以预防原发性感染和这种复杂的过程(包括费用)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Leptospirosis due to occupational activity in a sewage treatment plant - case report of a recognized occupational disease].

The patient (male, two expert reports: 61 and 63 years old) experienced symptoms of a flu-like infection with rapid deterioration and cognitive complaints. He has been an employee of the municipal building yard with a sewage treatment plant for approximately 24 years.Acute renal insufficiency (creatinine 9.7 mg/dl), increased anti-Leptospira IgM antibodies and Leptospira DNA using PCR were detected. The CT neurocranium without contrast medium did not reveal any relevant abnormalities.Sepsis with multiorgan failure including a type 2 myocardial infarction and acute renal failure in the context of leptospirosis was diagnosed.Antibiotic therapies with piperacillin/tazobactam, clarithromycin and meropenem were given. Regarding acute renal failure, renal function was significantly improved by using temporary hemodialysis. After an assessment, leptospirosis was recognized as occupational disease No. 3102 in accordance with Appendix 1 of the Occupational Diseases Ordinance.Physicians should take a work history and, if there is reasonable suspicion, are legally obliged to report suspected occupational diseases. The primary infection and such a complex course (including costs) can be prevented by adequate occupational safety.

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