{"title":"微生物领头羊：社区规模代谢模型预测感染。","authors":"Connor Tiffany, Joseph P Zackular","doi":"10.1016/j.cels.2025.101370","DOIUrl":null,"url":null,"abstract":"<p><p>Microbial colonization is shaped by a complex network of interactions that influence both commensals and pathogens, including the public-health threat Clostridioides difficile. In this issue of Cell Systems, Carr et al. present a community-scale modeling framework for predicting colonization and metabolism, offering new insights into C. difficile infection.</p>","PeriodicalId":93929,"journal":{"name":"Cell systems","volume":"16 8","pages":"101370"},"PeriodicalIF":7.7000,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Microbial bellwether: Community-scale metabolic modeling to predict infection.\",\"authors\":\"Connor Tiffany, Joseph P Zackular\",\"doi\":\"10.1016/j.cels.2025.101370\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Microbial colonization is shaped by a complex network of interactions that influence both commensals and pathogens, including the public-health threat Clostridioides difficile. In this issue of Cell Systems, Carr et al. present a community-scale modeling framework for predicting colonization and metabolism, offering new insights into C. difficile infection.</p>\",\"PeriodicalId\":93929,\"journal\":{\"name\":\"Cell systems\",\"volume\":\"16 8\",\"pages\":\"101370\"},\"PeriodicalIF\":7.7000,\"publicationDate\":\"2025-08-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.cels.2025.101370\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.cels.2025.101370","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Microbial bellwether: Community-scale metabolic modeling to predict infection.
Microbial colonization is shaped by a complex network of interactions that influence both commensals and pathogens, including the public-health threat Clostridioides difficile. In this issue of Cell Systems, Carr et al. present a community-scale modeling framework for predicting colonization and metabolism, offering new insights into C. difficile infection.
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