在子宫内暴露于极端高温会增加新生儿死亡率。

IF 3.8 Q2 MULTIDISCIPLINARY SCIENCES
PNAS nexus Pub Date : 2025-08-19 eCollection Date: 2025-08-01 DOI:10.1093/pnasnexus/pgaf240
Tenghui Wang, Jiafu An, Bin Chen, Chris John Webster, Peng Gong, Chen Lin
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引用次数: 0

摘要

在过去的几十年里,撒哈拉以南非洲地区的新生儿死亡率是世界上最高的。2021年,撒哈拉以南非洲每千名活产婴儿中有27名在出生后第一个月内死亡,占非洲大陆婴儿死亡(0-12个月)的54%。与此同时,由于气候变化,该地区极端高温事件的发生频率越来越高,使本已脆弱的人群的生活和健康状况恶化。尽管撒哈拉以南非洲新生儿死亡率高且极端天气事件频繁发生,但尚不清楚子宫内暴露于极端高温是否是一个重要因素。我们的研究使用来自33个非洲国家的极端高温和出生记录的颗粒数据来调查这个问题,这些数据来自人口和健康调查。它每5年收集一次具有全国代表性的重复横断面调查,评估发展中国家的生殖和健康行为。采用同时考虑湿度影响的热量测量,我们表明,在9个月的怀孕期间,极端高温暴露累计增加150°C与每千名活产新生儿中增加两例新生儿死亡有关。经济地位较低或受教育程度有限的母亲受到极端高温的影响更为明显,这可能是由于产前护理减少所致。我们的研究结果与决策者有关,他们旨在通过更好地针对极端高温的受害者和制定有效的适应策略来遏制气候变化的负面影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
In utero exposure to extreme heat increases neonatal mortality.

Sub-Saharan Africa (SSA) has had the highest neonatal mortality rate in the world for the past few decades. In 2021, 27 infants died within the first month of life for every thousand live births in SSA, accounting for 54% of infant deaths (0-12 months) on the continent. Meanwhile, extreme heat events are occurring with increasingly higher frequency in this region due to climate change, worsening the living and health conditions for already vulnerable populations. Despite the prominence of high neonatal mortality rates and the frequent occurrence of extreme weather events in SSA, it remains unclear whether in-utero exposure to extreme heat is a significant contributing factor. Our research investigates this question using granular data on extreme heat and birth records from 33 African countries drawn from the Demographic and Health Surveys. It collects nationally representative, repeated cross-sectional surveys that assess reproductive and health behaviors across the developing countries every 5 years. Employing a measure of heat that simultaneously accounts for the impact of humidity, we show that a cumulative increase of 150 °C in extreme heat exposure during the 9-month pregnancy period is associated with two additional neonatal deaths per thousand live births. Mothers with lower economic status or limited education experience a more pronounced negative impact from exposure to extreme heat, likely due to reduced prenatal care. Our results are relevant to policymakers aiming to curb the negative impacts of climate change by better targeting the victims of extreme heat and developing effective adaptation strategies.

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